Revised Manuscript Received March 24, 1994• abstract: The photoactivatable aryl ketone
derivatives have been rediscovered as biochemical probes in the last 5 years. The …

Modification of proteins, DNA, and other biopolymers by labeling them with reporter
molecules has become a very powerful research tool in immunology, histochem-istry, and …

Diazirines are widely used in photoaffinity labeling (PAL) to trap noncovalent interactions
with biomolecules. However, design and interpretation of PAL experiments is challenging …

Chemical cross-linking reagents have attained great practical use in industry as well as in
basic research, and an understanding of their fundamental principles of reaction is …

Diazirines are three-membered ring systems containing two nitrogen atoms and one carbon
atom1, 2 widely applicable in biology as photoaffinity labeling agents. 3, 4 Diazirines can be …

Functionalized perfluorophenyl azides (PFPA) 2-6, 8-12, 14-19, and 21-29 were
synthesized, allowing the attachment of PFPA to other molecules for application as …

Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …

Investigation of receptor—ligand interactions remains an inexhaustible challenge for
chemists and biologists. Structural exploration of biological receptors is the starting point for …

This volume brings together all aspects of TAXOL® research, development, and clinical use.
It provides comprehensive knowledge of the compound and a perspective of the complex …

Photo-induced cross-linking (PIC) is a powerful strategy for generating information on
biomolecular interactions. In PIC, the utility of traditional cross-linking methods is …