Latency and lytic replication in Epstein–Barr virus-associated oncogenesis

C Münz - Nature Reviews Microbiology, 2019 - nature.com
Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is
primarily associated with lymphomas and epithelial cell cancers. These tumours express …

Epstein Barr virus and autoimmune responses in systemic lupus erythematosus

NR Jog, JA James - Frontiers in immunology, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease. Infections
or infectious reactivation are potential triggers for initiation of autoimmunity and for SLE …

Epstein‐Barr virus strain variation and cancer

T Kanda, M Yajima, K Ikuta - Cancer science, 2019 - Wiley Online Library
Epstein‐Barr virus (EBV) is a human tumor virus and is etiologically linked to various
malignancies. Certain EBV‐associated diseases, such as Burkitt lymphomas and …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Epstein–Barr virus: diseases linked to infection and transformation

HC Jha, Y Pei, ES Robertson - Frontiers in microbiology, 2016 - frontiersin.org
Epstein–Barr virus (EBV) was first discovered in 1964, and was the first known human tumor
virus now shown to be associated with a vast number of human diseases. Numerous studies …

Epstein–Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling

M Samanta, D Iwakiri, K Takada - Oncogene, 2008 - nature.com
Epstein–Barr virus-encoded small RNA (EBER) is nonpolyadenylated, noncoding RNA,
forms stem-loop structure by intermolecular base-pairing giving rise to double-stranded RNA …

Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing

T Tagawa, M Albanese, M Bouvet… - Journal of Experimental …, 2016 - rupress.org
Epstein-Barr virus (EBV) is a tumor virus that establishes lifelong infection in most of
humanity, despite eliciting strong and stable virus-specific immune responses. EBV encodes …

EBV noncoding RNAs

RL Skalsky, BR Cullen - Epstein Barr virus volume 2: one herpes virus …, 2015 - Springer
EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of
which have known regulatory functions and can post-transcriptionally regulate viral and/or …

Role of EBERs in the pathogenesis of EBV infection

D Iwakiri, K Takada - Advances in cancer research, 2010 - Elsevier
Abstract Epstein–Barr virus (EBV)-encoded small RNAs (EBERs) are noncoding RNAs that
are expressed abundantly in latently EBV-infected cells. Previous studies demonstrated that …

Epstein‐Barr virus and the pathogenesis of Burkitt's lymphoma: more questions than answers

GW Bornkamm - International journal of cancer, 2009 - Wiley Online Library
Burkitt's lymphoma (BL) was first described as a clinical entity in children in Central Africa by
Denis Burkitt in 1958. The particular epidemiological features of this tumor initiated the …