Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …

Elite athlete status is a partially heritable trait, as are many of the underpinning
physiological, anthropometrical, and psychological traits that contribute to elite performance …

Background Recent studies indicate important roles for long noncoding RNAs (lncRNAs) in
the regulation of gene expression by acting as competing endogenous RNAs (ceRNAs) …

Loss of muscle proteins and the consequent weakness has important clinical consequences
in diseases such as cancer, diabetes, chronic heart failure, and in aging. In fact, excessive …

Recent studies demonstrate the functions of long non-coding RNAs (lncRNAs) in mediating
gene expression at the transcriptional or translational level. Our previous study identified a …

Although many long noncoding RNAs (lncRNAs) have been identified in muscle, their
physiological function and regulatory mechanisms remain largely unexplored. In this study …

Circular RNAs (circRNAs) have been identified in numerous species, including human,
mouse, nematode, and coelacanth. They are believed to function as regulators of gene …

The transcription factor c-Myc is an important regulator of cellular proliferation, differentiation
and embryogenesis. While c-Myc can inhibit myoblast differentiation, the underlying …

The growth and development of skeletal muscle is regulated by proteins as well as non-
coding RNAs. Circular RNAs (circRNAs) are universally expressed in various tissues and …

The fusion of myoblasts is an important step during skeletal muscle differentiation. A recent
study in mice found that a transmembrane protein called Myomaker, which is specifically …