The history of antimicrobial resistance (AMR) evolution and the diversity of the
environmental resistome indicate that AMR is an ancient natural phenomenon. Acquired …

Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the γ-proteobacteria.
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …

Pseudomonas aeruginosa causes severe and persistent infections in immune compromised
individuals and cystic fibrosis sufferers. The infection is hard to eradicate as P. aeruginosa …

Formation of biofilm is a survival strategy for bacteria and fungi to adapt to their living
environment, especially in the hostile environment. Under the protection of biofilm, microbial …

Bacteria are highly interactive and possess an extraordinary repertoire of intercellular
communication and social behaviors, including quorum sensing (QS). QS has been studied …

The Pseudomonas quinolone signal (PQS) has been studied primarily in the context of its
role as a quorum-sensing signaling molecule. Recent data suggest, however, that this …

Antibiotics are chemotherapeutic agents, which have been a very powerful tool in the clinical
management of bacterial diseases since the 1940s. However, benefits offered by these …

Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

The introduction of antibiotics into clinical practice revolutionized the treatment and
management of infectious diseases. Before the introduction of antibiotics, these diseases …

This article gives a very brief overview of the antibiotic era, beginning from the discovery of
first antibiotics until the present day situation, which is marred by the emergence of hard-to …