Overview of PM2. 5 and health outcomes: focusing on components, sources, and pollutant mixture co-exposure

N Nan, Z Yan, Y Zhang, R Chen, G Qin, N Sang - Chemosphere, 2023 - Elsevier
PM 2.5 varies in source and composition over time and space as a complicated mixture.
Consequently, the health effects caused by PM 2.5 varies significantly over time and …

New insight into air pollution-related cardiovascular disease: an adverse outcome pathway framework of PM2.5-associated vascular calcification

R Ding, L Huang, K Yan, Z Sun… - Cardiovascular …, 2024 - academic.oup.com
Despite the air quality has been generally improved in recent years, ambient fine particulate
matter (PM2. 5), a major contributor to air pollution, remains one of the major threats to …

[HTML][HTML] Tetrahydrocurcumin regulates the tumor immune microenvironment to inhibit breast cancer proliferation and metastasis via the CYP1A1/NF-κB signaling …

A Zeng, X Yu, B Chen, L Hao, P Chen, X Chen… - Cancer Cell …, 2023 - Springer
The NF-κB signaling pathway is overactivated in tumor cells, and the activation of the NF-κB
signaling pathway releases a large number of inflammatory factors, which enhance tumor …

[HTML][HTML] Human biomonitoring and toxicokinetics as key building blocks for next generation risk assessment

E Reale, MZ Jeddi, A Paini, A Connolly, R Duca… - Environment …, 2024 - Elsevier
Human health risk assessment is historically built upon animal testing, often following
Organisation for Economic Co-operation and Development (OECD) test guidelines and …

PAHs as environmental pollutants and their neurotoxic effects

P Xu, B Liu, H Chen, H Wang, X Guo, J Yuan - … and Physiology Part C …, 2024 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs), which are widely present in incompletely
combusted air particulate matter< 2.5 μm (PM2. 5), tobacco and other organic materials, can …

AhR Agonistic Components in Urban Particulate Matter Regulate Astrocytic Activation and Function

Y Zhang, Y Pei, Y Sun, X Yang, J Liang… - Environmental …, 2024 - ACS Publications
Exposure to atmospheric particulate matter (PM) has been found to accelerate the onset of
neurological disorders via the induction of detrimental neuroinflammatory responses. To …

[HTML][HTML] Anti-Pollutant Activity of Porphyra yezoensis Water Extract and Its Active Compound, Porphyra 334, against Urban Particulate Matter-Induced Keratinocyte …

S Choi, JH Lee, SW Oh, E Yu, K Kwon, SJ Jang… - Marine Drugs, 2023 - mdpi.com
Urban particulate matter (UPM) causes skin aging and inflammatory reactions by influencing
skin cells through the aryl hydrocarbon receptor (AhR) signaling pathway. Porphyra …

Aryl hydrocarbon receptor-dependent toxicity by retene requires metabolic competence

CI Rude, LB Wilson, J La Du, PM Lalli… - Toxicological …, 2024 - academic.oup.com
Polycyclic aromatic hydrocarbons (PAHs) are a class of organic compounds frequently
detected in the environment with widely varying toxicities. Many PAHs activate the aryl …

RNA reading protein YTHDF2 mediates Benzo (k) fluoranthene induced male reproductive injury by regulating the stability of BCL2

Y Li, D Wang, H Chen, Y Zeng, N Wang, Y Shi, J Li… - Environmental …, 2024 - Elsevier
Abstract Benzo (k) fluoranthene (BkF) has adverse effects on male reproduction, but its
specific mechanism of action is still unclear. This study focused on the role of RNA reading …

Benzo (a) pyrene exposure impacts cerebrovascular development in zebrafish embryos and the antagonistic effect of berberine

K Xu, Q Wang, Y Zhang, Y Huang, Q Liu… - Science of The Total …, 2024 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) widely present in the environment, but their effect
on cerebrovascular development has been rarely reported. In this study, dechorionated …