[HTML][HTML] Atherosclerosis and cancer; a resemblance with far-reaching implications

JV Tapia-Vieyra, B Delgado-Coello… - Archives of medical …, 2017 - Elsevier
Atherosclerosis and cancer are chronic diseases considered two of the main causes of
death all over the world. Taking into account that both diseases are multifactorial, they share …

[HTML][HTML] Carbon nanomaterials for cardiovascular theranostics: Promises and challenges

KN Alagarsamy, S Mathan, W Yan, A Rafieerad… - Bioactive Materials, 2021 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Heart attack and
stroke cause irreversible tissue damage. The currently available treatment options are …

Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets

MP Vincent, S Bobbala, NB Karabin, M Frey… - Nature …, 2021 - nature.com
Controlling nanocarrier interactions with the immune system requires a thorough
understanding of the surface properties that modulate protein adsorption in biological fluids …

Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation

S Allen, O Osorio, YG Liu, E Scott - Journal of Controlled Release, 2017 - Elsevier
Flash nanoprecipitation (FNP) has proven to be a powerful tool for the rapid and scalable
assembly of solid-core nanoparticles from block copolymers. The process can be performed …

Tailoring nanostructure morphology for enhanced targeting of dendritic cells in atherosclerosis

S Yi, SD Allen, YG Liu, BZ Ouyang, X Li… - ACS …, 2016 - ACS Publications
Atherosclerosis, a leading cause of heart disease, results from chronic vascular
inflammation that is driven by diverse immune cell populations. Nanomaterials may function …

Plaque macrophage‐targeting nanosystems with cooperative Co‐regulation of ROS and TRAF6 for stabilization of atherosclerotic plaques

Q Yang, H Jiang, Y Wang, X Leng… - Advanced Functional …, 2023 - Wiley Online Library
Chronic inflammatory microenvironment is the predominant milieu that promotes the
progression of atherosclerosis (AS). However, targeted regulation of the chronic …

Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis

SD Allen, YG Liu, T Kim, S Bobbala, S Yi… - Biomaterials …, 2019 - pubs.rsc.org
In this work, the hydrophobic small molecule NF-κB inhibitor celastrol was loaded into poly
(ethylene glycol)-b-poly (propylene sulfide)(PEG-b-PPS) micelles. PEG-b-PPS micelles …

Sustained micellar delivery via inducible transitions in nanostructure morphology

NB Karabin, S Allen, HK Kwon, S Bobbala… - Nature …, 2018 - nature.com
Nanocarrier administration has primarily been restricted to intermittent bolus injections with
limited available options for sustained delivery in vivo. Here, we demonstrate that cylinder-to …

Nanoparticles: promising tools for the treatment and prevention of myocardial infarction

Q Pan, J Xu, CJ Wen, YY Xiong, ZT Gong… - International Journal of …, 2021 - Taylor & Francis
Despite several recent advances, current therapy and prevention strategies for myocardial
infarction are far from satisfactory, owing to limitations in their applicability and treatment …

On the advancement of polymeric bicontinuous nanospheres toward biomedical applications

SD Allen, S Bobbala, NB Karabin, EA Scott - Nanoscale horizons, 2019 - pubs.rsc.org
Self-assembled soft nanocarriers that are capable of simultaneous encapsulation of both
lipophilic and water soluble payloads have significantly enhanced controlled delivery …