In the last decade, RNA interference (RNAi), a cellular mechanism that uses RNA-guided
degradation of messenger RNA transcripts, has had an important impact on identifying and …

Structural synapses are key regulators of information flow in neuronal networks. To
understand the function and formation of neuronal circuits, the development and function of …

Axons are cable-like neuronal processes wiring the nervous system. They contain parallel
bundles of microtubules as structural backbones, surrounded by regularly spaced actin rings …

Behavioral circadian rhythms are controlled by a neuronal circuit consisting of diverse
neuronal subgroups. To understand the molecular mechanisms underlying the roles of …

The correct outgrowth of axons is essential for the development and regeneration of nervous
systems. Axon growth is primarily driven by microtubules. Key regulators of microtubules in …

Spectraplakins are large actin-microtubule linker molecules implicated in various processes,
including gastrulation, wound healing, skin blistering and neuronal degeneration …

A bewildering series of dynamical processes take part in the development of the nervous
system. Neuron branching dynamics, the continuous formation and elimination of neural …

Drosophila neurons have identifiable axons and dendrites based on cell shape, but it is only
just starting to become clear how Drosophila neurons are polarized at the molecular level …

While genetic screens have identified many genes essential for neurite outgrowth, they have
been limited in their ability to identify neural genes that also have earlier critical roles in the …

The mechanisms regulating synapse numbers during development and ageing are
essential for normal brain function and closely linked to brain disorders including dementias …