Recent progress in non-native nucleic acid modifications

LK McKenzie, R El-Khoury, JD Thorpe… - Chemical Society …, 2021 - pubs.rsc.org
While Nature harnesses RNA and DNA to store, read and write genetic information, the
inherent programmability, synthetic accessibility and wide functionality of these nucleic acids …

Mechanochemistry: opportunities for new and cleaner synthesis

SL James, CJ Adams, C Bolm, D Braga… - Chemical Society …, 2012 - pubs.rsc.org
The aim of this critical review is to provide a broad but digestible overview of
mechanochemical synthesis, ie reactions conducted by grinding solid reactants together …

Mechanochemical organic synthesis

GW Wang - Chemical Society Reviews, 2013 - pubs.rsc.org
Recently, mechanical milling using a mixer mill or planetary mill has been fruitfully utilized in
organic synthesis under solvent-free conditions. This review article provides a …

Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

D Tan, L Loots, T Friščić - Chemical Communications, 2016 - pubs.rsc.org
This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …

Ball milling in organic synthesis: solutions and challenges

A Stolle, T Szuppa, SES Leonhardt… - Chemical Society …, 2011 - pubs.rsc.org
During the last decade numerous protocols have been published using the method of ball
milling for synthesis all over the field of organic chemistry. However, compared to other …

Mechanochemistry for organic chemists: an update

D Tan, T Friščić - European Journal of Organic Chemistry, 2018 - Wiley Online Library
We provide a brief overview of recent advances in the use of mechanochemical techniques
for the synthesis of organic molecules and materials, highlighting selected examples of …

Salient achievements in synthetic organic chemistry enabled by mechanochemical activation

E Juaristi, CG Avila-Ortiz - Synthesis, 2023 - thieme-connect.com
Although known for millennia, it is only recently that mechanochemistry has received serious
attention by chemists. Indeed, during the past 15 years an extraordinary number of reports …

Solvent‐free and catalysts‐free chemistry: a benign pathway to sustainability

MB Gawande, VDB Bonifacio, R Luque… - …, 2014 - Wiley Online Library
In the past decade, alternative benign organic methodologies have become an imperative
part of organic syntheses and chemical reactions. The various new and innovative …

Metal-catalyzed organic reactions using mechanochemistry

JG Hernández, T Friščić - Tetrahedron Letters, 2015 - Elsevier
The past decade has witnessed an explosive growth of interest in mechanochemical
reactions by milling or grinding, and rapid expansion of mechanochemical methodologies …

Mechanochemical ruthenium-catalyzed olefin metathesis

JL Do, C Mottillo, D Tan, V Strukil… - Journal of the American …, 2015 - ACS Publications
We describe the development of a mechanochemical approach for Ru-catalyzed olefin
metathesis, including cross-metathesis and ring-closing metathesis. The method uses …