Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Magnetic particle imaging: tracer development and the biomedical applications of a radiation-free, sensitive, and quantitative imaging modality

S Harvell-Smith, NTK Thanh - Nanoscale, 2022 - pubs.rsc.org
Magnetic particle imaging (MPI) is an emerging tracer-based modality that enables real-time
three-dimensional imaging of the non-linear magnetisation produced by superparamagnetic …

The sensitivity of magnetic particle imaging and fluorine-19 magnetic resonance imaging for cell tracking

OC Sehl, PJ Foster - Scientific Reports, 2021 - nature.com
Magnetic particle imaging (MPI) and fluorine-19 (19F) MRI produce images which allow for
quantification of labeled cells. MPI is an emerging instrument for cell tracking, which is …

Systems Engineering Approach Towards Sensitive Cellular Fluorine‐19 MRI

J Chen, P Pal, ET Ahrens - NMR in Biomedicine, 2025 - Wiley Online Library
In vivo fluorine‐19 MRI using F‐based tracer media has shown utility and versatility for a
wide range of biomedical uses, particularly immune and stem cell detection, as well as …

In vivo tracking of adenoviral-transduced iron oxide-labeled bone marrow-derived dendritic cells using magnetic particle imaging

C Fink, JJ Gevaert, JW Barrett, JD Dikeakos… - European Radiology …, 2023 - Springer
Background Despite widespread study of dendritic cell (DC)-based cancer
immunotherapies, the in vivo postinjection fate of DC remains largely unknown. Due in part …

Investigation of the Post-Synthetic Confinement of Fluorous Liquids Inside Mesoporous Silica Nanoparticles

AL Lee, SH Lee, H Nguyen, M Cahill, E Kappel… - Langmuir, 2021 - ACS Publications
Perfluorocarbon (PFC) filled nanoparticles are increasingly being investigated for various
biomedical applications. Common approaches for PFC liquid entrapment involve surfactant …

Focused small field of view magnetic particle imaging for the detection and quantification of tumour associated macrophages

N Fernando, JJ Gevaert, J Konkle, P Goodwill… - bioRxiv, 2023 - biorxiv.org
Abstract Magnetic Particle Imaging (MPI) directly detects superparamagnetic iron oxide
(SPIO) labeled cells. We have used MPI to detect SPIO-labeled dendritic cells (DC) migrated …

Sensitivity and 19F MRI Cell Tracking

ET Ahrens - Fluorine Magnetic Resonance Imaging, 2025 - taylorfrancis.com
Although current generation materials and methods for 19F MRI show promise for detecting
therapeutic cell products and inflammation, next generation 19F technologies will have …

19F for Quantitative Tracking of Immune Cells Involved in Cancer Progression and Therapy

OC Sehl, AV Makela, PJ Foster - Fluorine Magnetic Resonance …, 2025 - taylorfrancis.com
The tumor microenvironment (TME) consists of cancer cells, stromal cells such as
fibroblasts, pericytes, endothelial cells and immune cells, as well as noncellular components …

Bioprocessing optimization to manufacture thymus-derived regulatory T cells for therapy

KN MacDonald - 2022 - open.library.ubc.ca
Regulatory T cell therapy has shown promise in treating autoimmune disorders, transplant
rejection and graft-versus-host disease in early clinical trials. However, efficient …