Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients

T Vogl, IN Kalka, S Klompus, S Leviatan… - Science …, 2022 - science.org
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with
an unclear etiology and pathogenesis. Both an involvement of the immune system and gut …

Patients with inflammatory bowel disease show IgG immune responses towards specific intestinal bacterial genera

AR Bourgonje, G Roo-Brand, P Lisotto… - Frontiers in …, 2022 - frontiersin.org
Introduction Inflammatory bowel disease (IBD) is characterized by a disturbed gut microbiota
composition. Patients with IBD have both elevated mucosal and serum levels of IgG …

Antibody signatures in inflammatory bowel disease: current developments and future applications

AR Bourgonje, T Vogl, E Segal, RK Weersma - Trends in molecular …, 2022 - cell.com
Adequate functioning of the intestinal barrier is required in order to repel invading
pathogens while tolerating commensal microbiota and self-antigens. Inflammatory bowel …

Phage Immunoprecipitation Sequencing (PhIP-Seq) for Analyzing Antibody Epitope Repertoires Against Food Antigens

I Filimonova, G Innocenti, T Vogl - Food Allergens: Methods and Protocols, 2023 - Springer
While thousands of food and environmental allergens have been reported, conventional
methods for allergy testing typically rely on measuring immunoglobulin E (IgE) binding …

Immune, metabolic, and microbial aspects of human health and aging

SA Sánchez - 2024 - research.rug.nl
Human disease is often associated with dysfunctions in the immune system or metabolism.
These dysfunctions are frequently linked to variations in the gut microbiome—the collection …