Synthetic aspects of metal‐catalyzed oxidations of amines and related reactions

SI Murahashi - Angewandte Chemie International Edition in …, 1995 - Wiley Online Library
The metabolism of amines is governed by a variety of enzymes such as amine oxidase,
flavoenzyme, and cytochrome P‐450. A wide variety of compounds are produced such as …

Organoselenium compounds: Chemistry and applications in organic synthesis

JM Sonego, SI De Diego, SH Szajnman… - … A European Journal, 2023 - Wiley Online Library
Selenium, originally described as a toxin, turns out to be a crucial trace element for life that
appears as selenocysteine and its dimer, selenocystine. From the point of view of drug …

Discovery of new selenoureido analogues of 4-(4-fluorophenylureido) benzenesulfonamide as carbonic anhydrase inhibitors

A Angeli, D Tanini, TS Peat… - ACS medicinal …, 2017 - ACS Publications
A series of benzenesulfonamides bearing selenourea moieties was obtained considering
the ureido-sulfonamide SLC-0111, in Phase I clinical trials as antitumor agent, as a lead …

Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates

AK Sharma, A Sharma, D Desai… - Journal of medicinal …, 2008 - ACS Publications
Synthesis and identification of novel phenylalkyl isoselenocyanates (ISCs), isosteric
selenium analogues of naturally occurring phenylalkyl isothiocyanates (ITCs), as effective …

Isoselenocyanates: a powerful tool for the synthesis of selenium-containing heterocycles

DR Garud, M Koketsu, H Ishihara - Molecules, 2007 - mdpi.com
Selenium-containing heterocyclic compounds have been well recognized, not only because
of their remarkable reactivities and chemical properties, but also because of their diverse …

Synthesis of sugar-derived isoselenocyanates, selenoureas, and selenazoles

O Lopez, S Maza, V Ulgar, I Maya… - Tetrahedron, 2009 - Elsevier
Aryl, alkyl, and sugar-derived isoselenocyanates were prepared by a one-pot procedure
starting from the corresponding formamides, using triphosgene as a dehydrating agent …

Development of isoselenocyanate compounds' syntheses and biological applications

EE Frieben, S Amin, AK Sharma - Journal of Medicinal Chemistry, 2019 - ACS Publications
As the number of cases and cancer-related deaths are projected to rise in upcoming years, it
is urgent to find ways to prevent or treat cancer. As such, food-derived products have gained …

Synthesis of O-unprotected glycosyl selenoureas. A new access to bicyclic sugar isoureas

JG Fernández-Bolaños, Ó López, V Ulgar, I Maya… - Tetrahedron letters, 2004 - Elsevier
β-d-Gluco and mannopyranosyl selenoureas have been prepared by coupling of the
corresponding glycosylamines with phenyl isoselenocyanate in aqueous pyridine. Alkyl and …

The Barton‐McCombie Reaction

SW McCombie, WB Motherwell, MJ Tozer - Organic Reactions, 2004 - Wiley Online Library
Deoxygenations of alcohols, ie, processes that replace a hydroxyl group with hydrogen at a
saturated carbon, find applications in both total synthesis and the systematic modifications of …

Direct hydrogen selenide (H 2 Se) release from activatable selenocarbamates

TD Newton, K Li, J Sharma, PA Champagne… - Chemical …, 2023 - pubs.rsc.org
Hydrogen selenide (H2Se) is a possible bioregulator, potential gasotransmitter, and
important precursor in biological organoselenium compound synthesis. Early tools for H2Se …