Pharmaceutical cocrystals: along the path to improved medicines
Cocrystals, a long known but understudied class of crystalline solids, have attracted interest
from crystal engineers and pharmaceutical scientists in the past decade and are now an …
from crystal engineers and pharmaceutical scientists in the past decade and are now an …
A practical guide to the design of molecular crystals
MK Corpinot, DK Bucar - Crystal Growth & Design, 2018 - ACS Publications
This Tutorial Review, aimed at both the novice and the seasoned solid-state chemist,
provides a succinct overview of key findings that have, over the last half century, advanced …
provides a succinct overview of key findings that have, over the last half century, advanced …
Challenges and opportunities of pharmaceutical cocrystals: a focused review on non-steroidal anti-inflammatory drugs
U Garg, Y Azim - RSC medicinal chemistry, 2021 - pubs.rsc.org
The focus of the review is to discuss the relevant and essential aspects of pharmaceutical
cocrystals in both academia and industry with an emphasis on non-steroidal anti …
cocrystals in both academia and industry with an emphasis on non-steroidal anti …
ROY reclaims its crown: new ways to increase polymorphic diversity
Chemical compounds that exist in multiple crystalline forms are said to exhibit
polymorphism. Polymorphs have the same composition, but their structures and properties …
polymorphism. Polymorphs have the same composition, but their structures and properties …
Co-crystallization and small molecule crystal form diversity: from pharmaceutical to materials applications
S Cherukuvada, R Kaur, TNG Row - CrystEngComm, 2016 - pubs.rsc.org
Co-crystallization is the supramolecular phenomenon of aggregation of two or more different
chemical entities in a crystalline lattice through non-covalent interactions. It encompasses …
chemical entities in a crystalline lattice through non-covalent interactions. It encompasses …
[HTML][HTML] Making crystals with a purpose; a journey in crystal engineering at the University of Bologna
The conceptual relationship between crystal reactivity, stability and metastability, solubility
and morphology on the one hand and shape, charge distribution, chirality and distribution of …
and morphology on the one hand and shape, charge distribution, chirality and distribution of …
A rough guide to molecular solid solutions: design, synthesis and characterization of mixed crystals
M Lusi - CrystEngComm, 2018 - pubs.rsc.org
Crystalline solid solutions are long-known solid phases that enable the fine tuning of a
material's structure and properties. Some of them, like metal alloys, have been employed in …
material's structure and properties. Some of them, like metal alloys, have been employed in …
Six-Component Molecular Solids: ABC[D1–(x+y)ExFy]2
M Paul, S Chakraborty, GR Desiraju - Journal of the American …, 2018 - ACS Publications
A strategy has been developed to achieve six-component molecular solids. The first part of
the protocol involves the design and development of a family of stoichiometric quaternary …
the protocol involves the design and development of a family of stoichiometric quaternary …
Curcumin, a biological wonder molecule: A crystal engineering point of view
Curcumin is a principal active ingredient of turmeric, extracted from the Curcuma longa
plant. The presence of several curcuminoids (eg, curcumin, demethoxycurcumin …
plant. The presence of several curcuminoids (eg, curcumin, demethoxycurcumin …
Seeking rules governing mixed molecular crystallization
Mixed crystals result when components of the structure are randomly replaced by analogues
in ratios that can be varied continuously over certain ranges. Mixed crystals are useful …
in ratios that can be varied continuously over certain ranges. Mixed crystals are useful …