Chromatin is highly dynamic, undergoing continuous global changes in its structure and
type of histone and DNA modifications governed by processes such as transcription, repair …

The third and fourth weeks of gestation in primates are marked by several developmental
milestones, including gastrulation and the formation of organ primordia. However, our …

Epithelial–mesenchymal transitions (EMTs) are the epitome of cell plasticity in embryonic
development and cancer; during EMT, epithelial cells undergo dramatic phenotypic changes …

We identify a population of Protogenin-positive (PRTG+ ve) MYC high NESTIN low stem
cells in the four-week-old human embryonic hindbrain that subsequently localizes to the …

Populations may adapt to similar environments via parallel or non‐parallel genetic changes,
but the frequency of these alternative mechanisms and underlying contributing factors are …

Individuals with mutations in CHD8 present with gastrointestinal complaints, yet the
underlying mechanisms are understudied. Here, using a stable constitutive chd8 mutant …

Epithelial to mesenchymal transition (EMT) is a well-defined cellular process that was
discovered in chicken embryos and described as “epithelial to mesenchymal …

The development of the vertebrate visual system involves complex morphogenetic
interactions of cells derived from multiple embryonic lineages. Disruptions in this process …

Epithelial–mesenchymal transition (EMT) is defined as a cellular process during which
epithelial cells acquire mesenchymal phenotypes and behavior following the …

The lateral plate mesoderm (LPM) is a transient tissue that produces a diverse range of
differentiated structures, including the limbs. However, the molecular mechanisms that drive …