Abstract The E, Z‐configured 1, 3‐diene unit is a common motif in numerous bioactive
natural products. Although several powerful methods are available to produce these motifs …

Stille reaction is one of the most common, efficient and selective Pd-catalyzed cross-
coupling reactions for the construction of CC bonds in the art of organic synthesis. It was …

Protein secretion in eukaryotes and prokaryotes involves a universally conserved protein
translocation channel formed by the Sec61 complex. Unrelated small-molecule natural …

Ipomoeassin F is a potent natural cytotoxin that inhibits growth of many tumor cell lines with
single-digit nanomolar potency. However, its biological and pharmacological properties …

A Ru-catalyzed conjugative isomerization of remote alkenes that affords branched 1, 3-
dienes is described. These kinetic products are obtained in high yields, good levels of …

The passion of total‐and fragments syntheses of natural products always remained one of
the top priorities among the synthetic chemists worldwide. Due their curiosity toward the …

The Mycobacterium ulcerans exotoxin, mycolactone, is responsible for the
immunosuppression and tissue necrosis that characterizes Buruli ulcer. Mycolactone inhibits …

Mycolactone is a complex macrolide toxin produced by Mycobacterium ulcerans, the
causative agent of Buruli ulcer. The aim of this paper is to review the chemistry, biosynthetic …

This is a review of papers published in the year 2017 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond …

Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is
caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A/B. In …