MicroRNAs in kidney injury and disease

N Mahtal, O Lenoir, C Tinel, D Anglicheau… - Nature Reviews …, 2022 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

MicroRNAs in AKI and kidney transplantation

KJ Ledeganck, EM Gielis, D Abramowicz… - Clinical Journal of the …, 2019 - journals.lww.com
MicroRNAs are epigenetic regulators of gene expression at the posttranscriptional level.
They are involved in intercellular communication and crosstalk between different organs. As …

[HTML][HTML] Single-cell analysis reveals immune landscape in kidneys of patients with chronic transplant rejection

Y Liu, J Hu, D Liu, S Zhou, J Liao, G Liao, S Yang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Single-cell RNA sequencing (scRNA-seq) has provided an unbiased assessment
of specific profiling of cell populations at the single-cell level. Conventional renal biopsy and …

microRNAs in kidney diseases: regulation, therapeutics, and biomarker potential

Z Liu, Y Fu, M Yan, S Zhang, J Cai, G Chen… - Pharmacology & …, 2024 - Elsevier
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in
regulating gene expression by inhibiting the translation of their specific target messenger …

Development and validation of urinary exosomal microRNA biomarkers for the diagnosis of acute rejection in kidney transplant recipients

JW Seo, YH Lee, DH Tae, YG Kim, JY Moon… - Frontiers in …, 2023 - frontiersin.org
Introduction Acute rejection (AR) continues to be a significant obstacle for short-and long-
term graft survival in kidney transplant recipients. Herein, we aimed to examine urinary …

Establishing biomarkers in transplant medicine: a critical review of current approaches

D Anglicheau, M Naesens, M Essig, W Gwinner… - …, 2016 - journals.lww.com
Although the management of kidney transplant recipients has greatly improved over recent
decades, the assessment of individual risks remains highly imperfect. Individualized …

Acute corneal transplant rejection after severe acute respiratory syndrome coronavirus 2 mRNA-1273 vaccination

S Yu, DC Ritterband, I Mehta - Cornea, 2022 - journals.lww.com
Purpose: The purpose of this article was to report a case of full-thickness corneal transplant
rejection 3 days after immunization with the severe acute respiratory syndrome coronavirus …

miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction

M Gigante, P Pontrelli, W Herr, M Gigante… - Journal of translational …, 2016 - Springer
Abstract Background Mammalian microRNAs (miR) regulate the expression of genes
relevant for the development of adaptive and innate immunity against cancer. Since T cell …

[HTML][HTML] Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature

DT Dugger, M Fung, SR Hays, JP Singer… - American Journal of …, 2021 - Elsevier
Chronic lung allograft dysfunction (CLAD) is the major barrier to long-term survival following
lung transplantation, and new mechanistic biomarkers are needed. Lymphocytic bronchitis …

Plasmacytoid dendritic cells promote acute kidney injury by producing interferon-α

B Deng, Y Lin, Y Chen, S Ma, Q Cai, W Wang… - Cellular & molecular …, 2021 - nature.com
Acute kidney injury (AKI) is a common clinical complication associated with high mortality in
patients. Immune cells and cytokines have recently been described to play essential roles in …