Background: Liver injury induced by drugs has become a primary reason for acute liver
disease and therefore posed a potential regulatory and clinical challenge over the past few …

Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other
neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ …

Pyridazinone analogues have been known to be potential candidates for anticonvulsant
agents. We have identified several pyridazinone-based anticonvulsant agents. As a …

The present study aims for the first time to provide the in vivo acute toxicological profile of the
highest dose of Clinacanthus nutans (Burm. f.) Lindau water leaf extract according to the …

Objectives: The ketogenic diet (KD) is a treatment for children with intractable epilepsy (IE),
can cause gastrointestinal symptoms, and have an adverse effect on growth, nutrition and …

Background Antiepileptic drugs are among the leading causes of drug-induced liver injury
(DILI). Due to critical illness, children admitted to intensive care units are more prone to DILI …

Background Liver injury associated with antiepileptic drugs accounts for a large proportion
of drug-induced liver injuries (DILI) in children. Although withdrawal of the causative agent is …

Cervical cancer, as the most frequent cancer in women globally and accounts almost 14% in
India. It can be prevented or treated with vaccines, radiation, chemotherapy, and …

Objectives: Sepsis is a clinical illness with a high rate of mortality all over the world.
Oxidative stress is considered the main phenomenon that occurs in sepsis. Rosa …

This study aimed to carry out a comparative study of the main models of chronic epilepsy
induced by pentylenetetrazole (PTZ)-kindling method and to assess the efficacy of sodium …