Role of PI3K/AKT pathway in cancer: the framework of malignant behavior
N Jiang, Q Dai, X Su, J Fu, X Feng, J Peng - Molecular biology reports, 2020 - Springer
Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …
Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression
M Quijada-Álamo, M Hernández-Sánchez… - Blood Cancer …, 2021 - nature.com
BIRC3 is monoallelically deleted in up to 80% of chronic lymphocytic leukemia (CLL) cases
harboring del (11q). In addition, truncating mutations in the remaining allele of this gene can …
harboring del (11q). In addition, truncating mutations in the remaining allele of this gene can …
UGT2B17 modifies drug response in chronic lymphocytic leukaemia
EP Allain, M Rouleau, K Vanura, S Tremblay… - British journal of …, 2020 - nature.com
Abstract Background High UGT2B17 is associated with poor prognosis in untreated chronic
lymphocytic leukaemia (CLL) patients and its expression is induced in non-responders to …
lymphocytic leukaemia (CLL) patients and its expression is induced in non-responders to …
Unexpected Insertion of Nitrogen into a C–C Bond: Access to 2, 3-Disubstituted Quinazolinone Scaffolds
HL Liu, XT Li, HZ Tian, XW Sun - Organic Letters, 2021 - ACS Publications
A novel, practical, highly efficient, and transition metal free nitrogen insertion reaction for the
synthesis of 2, 3-disubstituted quinazolinone derivatives was developed. Diverse …
synthesis of 2, 3-disubstituted quinazolinone derivatives was developed. Diverse …
Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells
Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia,
including chronic lymphocytic leukemia (CLL). VCX's role in apoptosis induction is well …
including chronic lymphocytic leukemia (CLL). VCX's role in apoptosis induction is well …
Chronic lymphocytic leukemia
T Vaisitti, F Arruga, A Ferrajoli - Cancers, 2020 - mdpi.com
This Special Issue of Cancers, made up of nine articles (four original papers, four reviews,
and a brief report), is dedicated to chronic lymphocytic leukemia (CLL). CLL is a monoclonal …
and a brief report), is dedicated to chronic lymphocytic leukemia (CLL). CLL is a monoclonal …