WD repeat-containing protein 5 (WDR5) is a member of the WD40 protein family, and it is
widely involved in various biological activities and not limited to epigenetic regulation in …

Protein complexes are vital to many biological processes and their understanding can lead
to the development of new drugs and therapies. Although the structure of individual protein …

The mortality rate from cervical cancer (CESC), a malignant tumor that affects women, has
increased significantly globally in recent years. The discovery of biomarkers points to a …

Diabetic retinopathy (DR) is a common consequence of diabetes mellitus and a primary
cause of visual impairment in middle-aged and elderly individuals. DR is susceptible to …

Globally, diabetes mellitus (DM) is one of the most occurred metabolic diseases, involving
an increased level of blood glucose in the body. In general, DM patients grow many …

Background Biologically data-driven networks have become powerful analytical tools that
handle massive, heterogeneous datasets generated from biomedical fields. Protein-protein …

Inflammasomes are pivotal cytosolic molecular platforms involved in infection resistance. As
multiprotein complexes, they consist of NOD-like receptors (NLRs), the adaptor proteins …

Pancreatic Cancer (PC) is the seventh leading cause of cancer-related death worldwide and
one of the deadliest malignant neoplasms. It is difficult to diagnose at an early stage. Lung …

Background: Bromodomains are a structurally conserved epigenetic reader domain that
bind to acetylated lysine residues in both histone and non-histone proteins. Bromodomain …

The nuclear pore complex (NPC) is the transport gateway of proteins, organic and inorganic
micromolecules, nucleic acids and mRNPs across the nuclear envelope. Additionally, it has …