Gender-and sex-based contributors to sex differences in PTSD

DM Christiansen, ET Berke - Current psychiatry reports, 2020 - Springer
Abstract Purpose of Review Sex differences in PTSD are well-established with a 2: 1 sex
ratio favouring women. Less well-established is the basis of such differences. The purpose …

[HTML][HTML] The role of estrogen receptors and their signaling across psychiatric disorders

WJ Hwang, TY Lee, NS Kim, JS Kwon - International journal of molecular …, 2020 - mdpi.com
Increasing evidence suggests estrogen and estrogen signaling pathway disturbances
across psychiatric disorders. Estrogens are not only crucial in sexual maturation and …

[HTML][HTML] Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals

PR Braun, S Han, B Hing, Y Nagahama… - Translational …, 2019 - nature.com
Differential DNA methylation in the brain is associated with many psychiatric diseases, but
access to brain tissues is essentially limited to postmortem samples. The use of surrogate …

Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders

MA Schiele, K Domschke - Genes, Brain and Behavior, 2018 - Wiley Online Library
The pathogenesis of anxiety disorders is multifactorial, involving complex interactions
between biological factors, environmental influences and psychological mechanisms …

Clinical advances in sex-and gender-informed medicine to improve the health of all: a review

D Bartz, T Chitnis, UB Kaiser… - JAMA internal …, 2020 - jamanetwork.com
Importance Biological sex and sociocultural gender represent major sources of diversity
among patients, and recent research has shown the association of sex and gender with …

Sex differences in schizophrenia, bipolar disorder, and post‐traumatic stress disorder: Are gonadal hormones the link?

A Gogos, LJ Ney, N Seymour… - British Journal of …, 2019 - Wiley Online Library
In this review, we describe the sex differences in prevalence, onset, symptom profiles, and
disease outcome that are evident in schizophrenia, bipolar disorder, and post‐traumatic …

Sex differences in fear responses: Neural circuits

EP Bauer - Neuropharmacology, 2023 - Elsevier
Women have increased vulnerability to PTSD and anxiety disorders compared to men.
Understanding the neurobiological underpinnings of these disorders is critical for identifying …

[HTML][HTML] Neurophysiology and psychopathology underlying PTSD and recent insights into the PTSD therapies—a comprehensive review

G Aliev, NM Beeraka, VN Nikolenko… - Journal of clinical …, 2020 - mdpi.com
Post-traumatic stress disorder (PTSD) is a well-known psychiatric disorder that affects
millions of people worldwide. Pharmacodynamic and cognitive-behavioral therapies (CBT) …

Mechanisms of sex differences in fear and posttraumatic stress disorder

TS Ramikie, KJ Ressler - Biological psychiatry, 2018 - Elsevier
Following sexual maturity, females disproportionately have higher rates of posttraumatic
stress disorder (PTSD) and experience greater symptom severity and chronicity as …

Women are taking the hit: examining the unique consequences of cannabis use across the female lifespan

EL Gräfe, HMO Reid, I Shkolnikov, K Conway… - Frontiers in …, 2023 - Elsevier
Cannabis use has risen dramatically in recent years due to global decriminalization and a
resurgence in the interest of potential therapeutic benefits. While emerging research is …