Adiponectin: Structure, physiological functions, role in diseases, and effects of nutrition
Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …
Microvascular dysfunction in diabetes mellitus and cardiometabolic disease
WB Horton, EJ Barrett - Endocrine reviews, 2021 - academic.oup.com
This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …
[HTML][HTML] Adiponectin, leptin, and fatty acids in the maintenance of metabolic homeostasis through adipose tissue crosstalk
Metabolism research has made tremendous progress over the last several decades in
establishing the adipocyte as a central rheostat in the regulation of systemic nutrient and …
establishing the adipocyte as a central rheostat in the regulation of systemic nutrient and …
Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies
P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …
life because of its associated complications, including diabetes, cardiovascular diseases …
Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis
VD D'Agati, A Chagnac, AP De Vries, M Levi… - Nature Reviews …, 2016 - nature.com
The prevalence of obesity-related glomerulopathy is increasing in parallel with the
worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal segmental …
worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal segmental …
Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization
Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but
detectable expression of adiponectin can be observed in cell types beyond adipocytes …
detectable expression of adiponectin can be observed in cell types beyond adipocytes …
Mechanisms of diabetic complications
It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …
required, but also for its major complications, affecting both small and large blood vessels …
Molecular mechanisms of diabetic kidney disease
K Reidy, HM Kang, T Hostetter… - The Journal of clinical …, 2014 - Am Soc Clin Investig
Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide and the
single strongest predictor of mortality in patients with diabetes. DKD is a prototypical disease …
single strongest predictor of mortality in patients with diabetes. DKD is a prototypical disease …
New insight into adiponectin role in obesity and obesity‐related diseases
E Nigro, O Scudiero, ML Monaco… - BioMed research …, 2014 - Wiley Online Library
Obesity is a major health problem strongly increasing the risk for various severe related
complications such as metabolic syndrome, cardiovascular diseases, respiratory disorders …
complications such as metabolic syndrome, cardiovascular diseases, respiratory disorders …
Evolving importance of kidney disease: from subspecialty to global health burden
In the past decade, kidney disease diagnosed with objective measures of kidney damage
and function has been recognised as a major public health burden. The population …
and function has been recognised as a major public health burden. The population …