The thalamus engages in various functions including sensory processing, attention, decision
making and memory. Classically, this diversity of function has been attributed to the nuclear …

Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …

Sensory perception depends on the context in which a stimulus occurs. Prevailing models
emphasize cortical feedback as the source of contextual modulation. However, higher order …

Studies of visual processing in rodents have conventionally been performed on
anesthetized animals, precluding examination of the effects of behavior on visually evoked …

Summary Cortical layer 5 (L5) pyramidal neurons integrate inputs from many sources and
distribute outputs to cortical and subcortical structures. Previous studies demonstrate two L5 …

How a sensory stimulus is processed and perceived depends on the surrounding sensory
scene. In the visual cortex, contextual signals can be conveyed by an extensive network of …

After entering the cerebral cortex, sensory information spreads through six different
horizontal neuronal layers that are interconnected by vertical axonal projections. It is …

Genetic methods available in mice are likely to be powerful tools in dissecting cortical
circuits. However, the visual cortex, in which sensory coding has been most thoroughly …

Vision is the sense humans rely on most to navigate the world, make decisions, and perform
complex tasks. Understanding how humans see thus represents one of the most …

To establish the mouse as a genetically tractable model for high-order visual processing, we
characterized fine-scale retinotopic organization of visual cortex and determined functional …