Diet and inflammation in cognitive ageing and Alzheimer's disease

AM McGrattan, B McGuinness, MC McKinley… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review Nutrition is known to modulate the immune system and may
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …

Cardiovascular comorbidities, inflammation, and cerebral small vessel disease

LE Evans, JL Taylor, CJ Smith… - Cardiovascular …, 2021 - academic.oup.com
Cerebral small vessel disease (cSVD) is the most common cause of vascular cognitive
impairment and affects all levels of the brain's vasculature. Features include diverse …

Alzheimer's disease and other neurodegenerative dementias in comorbidity: a clinical and neuropathological overview

R Matej, A Tesar, R Rusina - Clinical biochemistry, 2019 - Elsevier
Neuropathological diagnostic criteria of neurodegenerative disorders are based on the
presence of specific inclusions in a specific area of brain tissue that correlate with clinical …

Emerging biomarkers in vascular cognitive impairment and dementia: from pathophysiological pathways to clinical application

V Cipollini, F Troili, F Giubilei - International journal of molecular sciences, 2019 - mdpi.com
Vascular pathology is the second most common neuropathology of dementia after
Alzheimer's disease (AD), with small vessels disease (SVD) being considered the major …

[HTML][HTML] Dysfunction of the blood-brain barrier in cerebral microbleeds: from bedside to bench

H Wang, C Zhang, Y Qiu, A Chen, Y Li, B Hu - Aging and disease, 2021 - ncbi.nlm.nih.gov
Cerebral microbleeds (CMBs) are a disorder of cerebral microvessels that are characterized
as small (< 10 mm), hypointense, round or ovoid lesions seen on T2*-weighted gradient …

Cerebral small vessel disease (CSVD)–lessons from the animal models

M Mustapha, CMNCM Nassir, N Aminuddin… - Frontiers in …, 2019 - frontiersin.org
Cerebral small vessel disease (CSVD) refers to a spectrum of clinical and imaging findings
resulting from pathological processes of various etiologies affecting cerebral arterioles …

[HTML][HTML] Blood-based biomarkers of cerebral small vessel disease

LY Wu, YL Chai, IK Cheah, RSL Chia, S Hilal… - Ageing Research …, 2024 - Elsevier
Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

Contribution of inflammation and hypoperfusion to white matter hyperintensities-related cognitive impairment

CJ Huang, X Zhou, X Yuan, W Zhang, MX Li… - Frontiers in …, 2022 - frontiersin.org
White matter hyperintensities (WMHs) of presumed vascular origin are one of the most
important neuroimaging markers of cerebral small vessel disease (CSVD), which are closely …

Mediterranean diet and white matter hyperintensity change over time in cognitively intact adults

S Song, AM Gaynor, E Cruz, S Lee, Y Gazes, C Habeck… - Nutrients, 2022 - mdpi.com
Current evidence on the impact of Mediterranean diet (MeDi) on white matter hyperintensity
(WMH) trajectory is scarce. This study aims to examine whether greater adherence to MeDi …

Biomarkers involved in the pathogenesis of cerebral small-vessel disease

X Liu, P Sun, J Yang, Y Fan - Frontiers in neurology, 2022 - frontiersin.org
Cerebral small-vessel disease (CSVD) has been found to have a strong association with
vascular cognitive impairment (VCI) and functional loss in elderly patients. At present, the …