Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment

J Burgess, M Ferdousi, D Gosal, C Boon… - Oncology and …, 2021 - Springer
Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Mechanistic investigations of diabetic ocular surface diseases

Q Zhou, L Yang, Q Wang, Y Li, C Wei… - Frontiers in …, 2022 - frontiersin.org
With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

Early detection of diabetic peripheral neuropathy: a focus on small nerve fibres

J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis… - Diagnostics, 2021 - mdpi.com
Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

Artificial intelligence utilising corneal confocal microscopy for the diagnosis of peripheral neuropathy in diabetes mellitus and prediabetes

FG Preston, Y Meng, J Burgess, M Ferdousi, S Azmi… - Diabetologia, 2022 - Springer
Aims/hypothesis We aimed to develop an artificial intelligence (AI)-based deep learning
algorithm (DLA) applying attribution methods without image segmentation to corneal …

Corneal confocal microscopy predicts the development of diabetic neuropathy: a longitudinal diagnostic multinational consortium study

BA Perkins, LE Lovblom, EJH Lewis, V Bril… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE Corneal nerve fiber length (CNFL) has been shown in research studies to
identify diabetic peripheral neuropathy (DPN). In this longitudinal diagnostic study, we …

[HTML][HTML] Corneal confocal microscopy: a biomarker for diabetic peripheral neuropathy

IN Petropoulos, G Ponirakis, M Ferdousi, S Azmi… - Clinical …, 2021 - Elsevier
Purpose Diagnosing early diabetic peripheral neuropathy remains a challenge due to
deficiencies in currently advocated end points. The cornea is densely innervated with small …

[HTML][HTML] The ocular surface and diabetes, the other 21st Century epidemic

Y Bu, KC Shih, L Tong - Experimental Eye Research, 2022 - Elsevier
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by sustained
hyperglycemia, potentially leading to life-threatening health problems. While the …

Diabetic keratopathy: redox signaling pathways and therapeutic prospects

F Buonfiglio, J Wasielica-Poslednik, N Pfeiffer… - Antioxidants, 2024 - mdpi.com
Diabetes mellitus, the most prevalent endocrine disorder, not only impacts the retina but also
significantly involves the ocular surface. Diabetes contributes to the development of dry eye …

Diabetic corneal neuropathy: pathogenic mechanisms and therapeutic strategies

T Zhou, A Lee, ACY Lo, JSWJ Kwok - Frontiers in Pharmacology, 2022 - frontiersin.org
Diabetes mellitus (DM) is a major global public health problem that can cause complications
such as diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. Besides the …