Post-translational modifications (PTMs) of histone proteins are a hallmark of epigenetic
regulation. They provide a mechanism to modulate chromatin structure and constitute the …

Plasticity in the brain is important for learning and memory, and allows us to respond to
changes in the environment. Furthermore, long periods of stress can lead to structural and …

In skeletal muscle, asymmetrically dividing satellite stem cells give rise to committed satellite
cells that transcribe the myogenic determination factor Myf5, a Pax7-target gene. We …

Transcriptional coregulators (coactivators and corepressors) have emerged as the principal
modulators of the functions of nuclear receptors and other transcription factors. During the …

Arginine methylation has been implicated in the regulation of gene expression. The
coactivator-associated arginine methyltransferase 1 (CARM1/PRMT4) binds the p160 family …

Introduction: Arginine methylation is an abundant posttranslational modification occurring in
mammalian cells and catalyzed by protein arginine methyltransferases (PRMTs) …

Epigenetic processes are essential for normal development and the maintenance of tissue-
specific gene expression in mammals. Changes in gene expression and malignant cellular …

Abstract Information about the family of protein arginine methyltransferases (PRMTs) has
been growing rapidly over the last few years and the emerging role of arginine methylation …

Introduction 3. Role of histone arginine methylation in gene regulation 3.1. Protein arginine
methyltransferases catalyze histone arginine methylation 3.2. Transcriptional activation …

Abstract Protein arginine methyltransferase (PRMT) 4 (also known as coactivator-associated
arginine methyltransferase 1; CARM1) is involved in a variety of biological processes and is …