[HTML][HTML] Peripheral neuropathy in diabetes mellitus: pathogenetic mechanisms and diagnostic options

R Galiero, A Caturano, E Vetrano, D Beccia… - International Journal of …, 2023 - mdpi.com
Diabetic neuropathy (DN) is one of the main microvascular complications of both type 1 and
type 2 diabetes mellitus. Sometimes, this could already be present at the time of diagnosis …

[HTML][HTML] Prevention and management strategies for diabetic neuropathy

S Smith, P Normahani, T Lane… - Life, 2022 - mdpi.com
Diabetic neuropathy (DN) is a common complication of diabetes that is becoming an
increasing concern as the prevalence of diabetes rapidly rises. There are several types of …

[HTML][HTML] Artificial intelligence utilising corneal confocal microscopy for the diagnosis of peripheral neuropathy in diabetes mellitus and prediabetes

FG Preston, Y Meng, J Burgess, M Ferdousi, S Azmi… - Diabetologia, 2022 - Springer
Aims/hypothesis We aimed to develop an artificial intelligence (AI)-based deep learning
algorithm (DLA) applying attribution methods without image segmentation to corneal …

[HTML][HTML] The ocular surface and diabetes, the other 21st Century epidemic

Y Bu, KC Shih, L Tong - Experimental Eye Research, 2022 - Elsevier
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by sustained
hyperglycemia, potentially leading to life-threatening health problems. While the …

High-frequency spinal cord stimulation (10 kHz) alters sensory function and nerve fiber density in painful diabetic neuropathy: a pilot prospective open-label study

J Chen, K Frizzi, S Zardouz, R Province-Azalde… - Pain …, 2023 - academic.oup.com
Objective Spinal cord stimulation at 10 kHz has provided effective pain relief and improved
function in painful diabetic peripheral neuropathy. This study aims to confirm the clinical …

[HTML][HTML] Effects of oral alpha-lipoic acid treatment on diabetic polyneuropathy: a meta-analysis and systematic review

RY Hsieh, IC Huang, C Chen, JY Sung - Nutrients, 2023 - mdpi.com
Alpha-lipoic acid (ALA) was found to improve the symptoms in patients with diabetic
sensorimotor peripheral neuropathy (DSPN) by reducing oxidative stress and ameliorating …

[HTML][HTML] Artificial intelligence and corneal confocal microscopy: the start of a beautiful relationship

U Alam, M Anson, Y Meng, F Preston, V Kirthi… - Journal of Clinical …, 2022 - mdpi.com
Corneal confocal microscopy (CCM) is a rapid non-invasive in vivo ophthalmic imaging
technique that images the cornea. Historically, it was utilised in the diagnosis and clinical …

[HTML][HTML] Effects of 1, 25-Vitamin D3 and 24, 25-Vitamin D3 on Corneal Nerve Regeneration in Diabetic Mice

X Lu, Z Chen, J Lu, MA Watsky - Biomolecules, 2023 - mdpi.com
Corneal nerve homeostasis is essential for the functional integrity of the ocular surface.
Vitamin D deficiency (VDD) and vitamin D receptor knockout (VDR KO) have been found to …

[HTML][HTML] Corneal sensitivity is inversely correlated with severity of diabetic retinopathy in a predominantly underrepresented population

M Singer, P O'Brien, L Mein, A Olvera - American Journal of Ophthalmology, 2024 - Elsevier
PURPOSE To assess the relationship between diabetic retinopathy (DR) and corneal
sensitivity. METHODS In this prospective study, 100 eyes of 50 patients from primarily …

[HTML][HTML] Disrupted Neural Regeneration in Dry Eye Secondary to Ankylosing Spondylitis—With a Theoretical Link between Piezo2 Channelopathy and Gateway …

B Sonkodi, L Marsovszky, A Csorba, A Balog… - International Journal of …, 2023 - mdpi.com
This study aimed at analyzing the corneal neural regeneration in ankylosing spondylitis
patients using in vivo corneal confocal microscopy in correlation with Langerhans cell …