Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Magnetic susceptibility describes the magnetizability of a material to an applied magnetic
field and represents an important parameter in the field of MRI. With the recently introduced …

We present a publicly available dataset of 227 healthy participants comprising a young (N=
153, 25.1±3.1 years, range 20–35 years, 45 female) and an elderly group (N= 74, 67.6±4.7 …

Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

Deep neural networks have demonstrated promising potential for the field of medical image
reconstruction, successfully generating high quality images for CT, PET and MRI. In this …

Purpose The aim of the 2016 quantitative susceptibility mapping (QSM) reconstruction
challenge was to test the ability of various QSM algorithms to recover the underlying …

Although iron is crucial for neuronal functioning, many aspects of cerebral iron biology await
clarification. The ability to quantify specific iron forms in the living brain would open new …

Background Quantitative susceptibility mapping (QSM) and R2* relaxation rate mapping
have demonstrated increased iron deposition in the substantia nigra of patients with …

Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis (MS) and have implications for non-relapsing biological progression. In …