Heme is an essential molecule expressed ubiquitously all through our tissues. Heme plays
major functions in cellular physiology and metabolism as the prosthetic group of diverse …

Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders
of the kidney in various etiologies, which significantly affect human survival and social …

Ferroptosis is a newly identified form of regulated cell death driven by iron-dependent
phospholipid peroxidation and oxidative stress. Ferroptosis has distinct biological and …

Significance: Acute kidney injury (AKI) and chronic kidney disease (CKD) represent a
considerable burden in healthcare. The heme oxygenase (HO) system plays an important …

Curcumin, a polyphenol derived from the turmeric, has received attention as a potential
treatment for renal fibrosis primarily because it is a relatively safe and inexpensive …

Scope Ochratoxin A (OTA) is a mycotoxin exhibiting nephrotoxic and potential carcinogenic
activity. We investigated the cross‐talk between micro RNA s, nuclear factor E 2‐related …

Background and Purpose Asthma is an inflammatory disease that involves airway
hyperresponsiveness and remodelling. Flavonoids have been associated to anti …

TGF-β plays a key role in the development of renal fibrosis. Suppressing the TGF-β signaling
pathway is a possible therapeutic approach for preventing this disease, and reports have …

Tubule-interstitial nephritis (TIN) results in decreased renal function and interstitial
inflammation, which ultimately leads to fibrosis. Excessive adenine intake can cause TIN …

Chronic kidney disease (CKD) is one of the most prevalent chronic diseases and affects
between 10 and 14% of the world's population. The World Health Organization estimates …