Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of
living organisms. In fact, AMPs have ability to incite the innate immune response and combat …

Abstract Development of successful production strategies for recombinant proteins is a
challenging task due to problems associated with the scale‐up of bioprocesses. Recent …

We report pyruvate formation in Escherichia coli strain ALS929 containing mutations in the
aceEF, pfl, poxB, pps, and ldhA genes which encode, respectively, the pyruvate …

The demand for therapeutic recombinant proteins is set to see a significant increase over the
next few years. As a consequence, the processes used to produce these proteins must be …

This paper reviews recent strategies used for increasing specific yield and productivity in
high cell density cultures. High cell density cultures offer an efficient means for the …

High-level production of α-cyclodextrin glycosyltransferase (CGTase) is one of the key
factors in α-cyclodextrin (CD) preparation. In the present study, a fed-batch fermentation …

This work aims to achieve the overproduction of alkaline polygalacturonate lyase (PGL) with
recombinant Escherichia coli by a two-stage glycerol feeding approach. First, the PGL …

The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells
has revolutionized the treatment of numerous diseases, solidifying their position as a …

Bioreactor processes have to provide an almost optimal environment to microorganisms or
cells to promote growth and product formation. The design and operation of a bioreactor as …

Background: The protein hormone granulocyte colony-stimulating factor (GCSF) stimulates
the production of white blood cells and plays an important role in medical treatment of …