Although immunotherapy research to date has focused largely on T cells, there is mounting
evidence that tumour-infiltrating B cells and plasma cells (collectively referred to as tumour …

The development of combination immunotherapy based on the mediation of regulatory
mechanisms of the tumor immune microenvironment (TIME) is promising. However, a deep …

Tertiary lymphoid structures (TLS) are transient ectopic lymphoid aggregates whose
formation might be caused by chronic inflammation states, such as cancer. However, how …

Tertiary lymphoid structures (TLS) are transient ectopic lymphoid aggregates where
adaptive antitumour cellular and humoral responses can be elaborated. Initially described in …

Tertiary lymphoid structures (TLSs) are associated with enhanced immunity in tumors.
However, their formation and functions in colorectal cancer liver metastasis (CRLM) remain …

B cells constitute a major component of infiltrating immune cells in colorectal cancer (CRC).
However, the characteristics of B cells and their clinical significance remain unclear. In this …

Tertiary lymphoid structures are immune cell aggregates linked with cancer outcomes, but
their interactions with tumour cell aggregates are unclear. Using nasopharyngeal carcinoma …

The tumor microenvironment (TME) directly determines patients' outcomes and therapeutic
efficiencies. An in‐depth understanding of the TME is required to improve the prognosis of …

Tertiary lymphoid structures (TLSs) are formed in inflamed tissues, and recent studies
demonstrated that the appearance of TLSs in tumor sites is associated with a good …

Tertiary lymphoid structures (TLSs) are defined as lymphoid aggregates formed in non-
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …