Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
Materials design by synthetic biology
Synthetic biology applies genetic tools to engineer living cells and organisms analogous to
the programming of machines. In materials synthetic biology, engineering principles from …
the programming of machines. In materials synthetic biology, engineering principles from …
Physical and chemical factors influencing the printability of hydrogel-based extrusion bioinks
SC Lee, G Gillispie, P Prim, SJ Lee - Chemical reviews, 2020 - ACS Publications
Bioprinting researchers agree that “printability” is a key characteristic for bioink
development, but neither the meaning of the term nor the best way to experimentally …
development, but neither the meaning of the term nor the best way to experimentally …
Application of “click” chemistry in biomedical hydrogels
X Li, Y Xiong - ACS omega, 2022 - ACS Publications
Since “click” chemistry was first reported in 2001, it has remained a popular research topic in
the field of chemistry due to its high yield without byproducts, fast reaction rate, simple …
the field of chemistry due to its high yield without byproducts, fast reaction rate, simple …
Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization
Virus-like particles (VLPs) are non-infectious self-assembling nanoparticles, useful in
medicine and nanotechnology. Their repetitive molecularly-defined architecture is attractive …
medicine and nanotechnology. Their repetitive molecularly-defined architecture is attractive …
Approaching infinite affinity through engineering of peptide–protein interaction
AH Keeble, P Turkki, S Stokes… - Proceedings of the …, 2019 - National Acad Sciences
Much of life's complexity depends upon contacts between proteins with precise affinity and
specificity. The successful application of engineered proteins often depends on high-stability …
specificity. The successful application of engineered proteins often depends on high-stability …
Power to the protein: enhancing and combining activities using the Spy toolbox
AH Keeble, M Howarth - Chemical Science, 2020 - pubs.rsc.org
Proteins span an extraordinary range of shapes, sizes and functionalities. Therefore generic
approaches are needed to overcome this diversity and stream-line protein analysis or …
approaches are needed to overcome this diversity and stream-line protein analysis or …
Achieving controlled biomolecule–biomaterial conjugation
The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …
modulate specific cell behaviors. While the biological roles of particular polypeptide …
Biomaterials and engineered microenvironments to control YAP/TAZ-dependent cell behaviour
G Brusatin, T Panciera, A Gandin, A Citron, S Piccolo - Nature materials, 2018 - nature.com
Mechanical signals are increasingly recognized as overarching regulators of cell behaviour,
controlling stemness, organoid biology, tissue development and regeneration. Moreover …
controlling stemness, organoid biology, tissue development and regeneration. Moreover …
Programmable polyproteams built using twin peptide superglues
G Veggiani, T Nakamura, MD Brenner… - Proceedings of the …, 2016 - National Acad Sciences
Programmed connection of amino acids or nucleotides into chains introduced a revolution in
control of biological function. Reacting proteins together is more complex because of the …
control of biological function. Reacting proteins together is more complex because of the …