The preservation of articular cartilage depends on keeping the cartilage architecture intact.
Cartilage strength and function depend on both the properties of the tissue and on their …

Despite the multifactorial nature of musculoskeletal disease, obesity consistently emerges
as a key and potentially modifiable risk factor in the onset and progression of …

OBJECTIVE: The role of inflammation in osteoarthritis (OA) pathogenesis is unclear, and the
associations between inflammatory cytokines and cartilage loss have not been reported. We …

Importance Observational studies suggest that vitamin D supplementation is associated with
benefits for knee osteoarthritis, but current trial evidence is contradictory. Objective To …

OBJECTIVE: Magnetic resonance imaging (MRI) is a three-dimensional imaging technique
with unparalleled ability to evaluate articular cartilage. This report reviews the current status …

The effects of exercise on articular hyaline articular cartilage have traditionally been
examined in animal models, but until recently little information has been available on human …

Despite acknowledgement in the scientific community of sex-based differences in cartilage
biology, the implications for study design remain unclear, with many studies continuing to …

Magnetic resonance imaging (MRI) and quantitative image analysis technology has recently
started to generate a great wealth of quantitative information on articular cartilage and bone …

Exercise remains an extremely popular leisure time activity in many countries throughout the
western world. It is widely promoted in the lay press as having salutory benefits for weight …

OBJECTIVE: To generate hypotheses regarding the associations between knee cartilage
defects and knee radiographic osteoarthritis (ROA), cartilage volume, bone size and type II …