A decade of discovery and development of new anti-malarial medicines has led to a
renewed focus on malaria elimination and eradication. Changes in the way new anti …

At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

Drinking water contamination with heavy metals, particularly lead, is a persistent problem
worldwide with grave public health consequences. Existing purification methods often …

Despite substantial scientific progress over the past two decades, malaria remains a
worldwide burden that causes hundreds of thousands of deaths every year. New, affordable …

Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

As part of the global effort toward malaria eradication, phenotypic whole-cell screening
revealed the 2-aminopyridine class of small molecules as a good starting point to develop …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load
and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for …

Antimicrobial treatment failure threatens our ability to control infections. In addition to
antimicrobial resistance, treatment failures are increasingly understood to derive from cells …

Plasmodium vivax malaria is characterized by periodic relapses of symptomatic blood stage
parasite infections likely initiated by activation of dormant liver stage parasites …