Modified internucleoside linkages for nuclease-resistant oligonucleotides
G Clavé, M Reverte, JJ Vasseur, M Smietana - RSC Chemical Biology, 2021 - pubs.rsc.org
In the past few years, several drugs derived from nucleic acids have been approved for
commercialization and many more are in clinical trials. The sensitivity of these molecules to …
commercialization and many more are in clinical trials. The sensitivity of these molecules to …
Nuclease stability of boron-modified nucleic acids: application to label-free mismatch detection
M Reverte, JJ Vasseur, M Smietana - Organic & Biomolecular …, 2015 - pubs.rsc.org
5′-End boronic acid-modified oligonucleotides were evaluated against various nucleases
at single and double stranded levels. The results show that these modifications induce a …
at single and double stranded levels. The results show that these modifications induce a …
[PDF][PDF] Обнаружение и характеристика некодирующих РНК в рибосомном межгенном спейсере человека
ГВ Павлова - genebiology.ru
Рибосомные гены, кодирующие рибосомные РНК (рРНК)–главные компоненты
рибосом, играют важную роль в обеспечении жизнедеятельности клеток организма …
рибосом, играют важную роль в обеспечении жизнедеятельности клеток организма …
[图书][B] Mimicking the action of ribonucleases: studies on RNase A and design of PNA based artificial enzymes
A Ghidini - 2015 - search.proquest.com
Abstract A 3'-deoxy-3'-C-methylenephosphonate modified diribonucleotide is highly
resistant to degradation by spleen phosphodiesterase and not cleaved at all by snake …
resistant to degradation by spleen phosphodiesterase and not cleaved at all by snake …