A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research

ML Phillips, HA Swartz - American Journal of Psychiatry, 2014 - Am Psychiatric Assoc
Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Structural connectomics in brain diseases

A Griffa, PS Baumann, JP Thiran, P Hagmann - Neuroimage, 2013 - Elsevier
Imaging the connectome in vivo has become feasible through the integration of several
rapidly developing fields of science and engineering, namely magnetic resonance imaging …

Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega-and meta-analyses across 3033 individuals

P Favre, M Pauling, J Stout, F Hozer… - …, 2019 - nature.com
Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the
pathophysiology of bipolar disorder (BD); however, diffusion tensor imaging (DTI) studies …

A unified model of the pathophysiology of bipolar disorder

P Magioncalda, M Martino - Molecular Psychiatry, 2022 - nature.com
This work provides an overview of the most consistent alterations in bipolar disorder (BD),
attempting to unify them in an internally coherent working model of the pathophysiology of …

Connectomics of bipolar disorder: a critical review, and evidence for dynamic instabilities within interoceptive networks

A Perry, G Roberts, PB Mitchell, M Breakspear - Molecular psychiatry, 2019 - nature.com
The notion that specific cognitive and emotional processes arise from functionally distinct
brain regions has lately shifted toward a connectivity-based approach that emphasizes the …

Abnormal dynamic functional network connectivity in unmedicated bipolar and major depressive disorders based on the triple-network model

J Wang, Y Wang, H Huang, Y Jia, S Zheng… - Psychological …, 2020 - cambridge.org
BackgroundPrevious studies have analyzed brain functional connectivity to reveal the
neural physiopathology of bipolar disorder (BD) and major depressive disorder (MDD) …

[HTML][HTML] Disturbed resting state EEG synchronization in bipolar disorder: a graph-theoretic analysis

DJ Kim, AR Bolbecker, J Howell, O Rass, O Sporns… - NeuroImage: Clinical, 2013 - Elsevier
Disruption of functional connectivity may be a key feature of bipolar disorder (BD) which
reflects disturbances of synchronization and oscillations within brain networks. We …

Functional dysconnection of the inferior frontal gyrus in young people with bipolar disorder or at genetic high risk

G Roberts, A Lord, A Frankland, A Wright, P Lau… - Biological …, 2017 - Elsevier
Background Bipolar disorder (BD) is characterized by a dysregulation of affect and impaired
integration of emotion with cognition. These traits are also expressed in probands at high …

Topologically convergent and divergent functional connectivity patterns in unmedicated unipolar depression and bipolar disorder

Y Wang, J Wang, Y Jia, S Zhong, M Zhong… - Translational …, 2017 - nature.com
Bipolar disorder (BD), particularly BD II, is frequently misdiagnosed as unipolar depression
(UD), leading to inappropriate treatment and poor clinical outcomes. Although depressive …

A multicenter tractography study of deep white matter tracts in bipolar I disorder: psychotic features and interhemispheric disconnectivity

S Sarrazin, C Poupon, J Linke, M Wessa… - JAMA …, 2014 - jamanetwork.com
Importance Tractography studies investigating white matter (WM) abnormalities in patients
with bipolar disorder have yielded heterogeneous results owing to small sample sizes. The …