According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

Background Frailty in older people is a syndrome related to aging that is becoming
increasingly common and problematic as the average age of the world population …

Background Frailty is a dynamic and complex geriatric condition characterized by multi-
domain declines in physiological, gait and cognitive function. This study examined whether …

Dealing with missing data is an important problem in statistical analysis that is often
addressed with imputation procedures. The performance and validity of such methods are of …

Background Poor functional status is a key marker of morbidity, yet is not routinely captured
in clinical encounters. We developed and evaluated the accuracy of a machine learning …

Background Dementia is a leading cause of disability in people older than 65 years
worldwide. However, diagnosing dementia in its earliest symptomatic stages remains …

Purpose We aimed to determine the best machine learning (ML) regression model for
predicting grip strength in adults above 65 years using various independent variables, such …

Understanding risk factors for frailty, functional decline and incidence of adverse healthcare
outcomes amongst community-dwelling older adults is important to plan population-level …

Prevention and diagnosis of frailty syndrome (FS) in patients with heart failure (HF) require
innovative systems to help medical personnel tailor and optimize their treatment and care …

The population is aging, and the biology of aging is conducive to both the development of
cardiovascular disease (CVD) as well as frailty, such that a bidirectional relationship exists …