Proteosomes based on milk phospholipids and proteins to enhance the stability and bioaccessibility of β-carotene

B Zarif, S Shabbir, R Shahid, T Noor, M Imran - Food Chemistry, 2023 - Elsevier
Proteosomes (P) based on milk fat globule membrane's phospholipids (MPs), whey protein
isolate (WPI) and sodium caseinate (CasNa) were developed by ultrasonication to …

[HTML][HTML] Advances in tailored drug delivery systems: Amphiphilic lyotropic mesomorphs for targeted therapeutic intervention

U Likhitha, UY Nayak - Journal of Molecular Liquids, 2024 - Elsevier
Amphiphilic molecules when dissolved in specific solvents form lyotropic mesomorphs with
unique crystalline structures and properties. The amphiphilic nature and supramolecular …

Advancements in nanoscale delivery systems: optimizing intermolecular interactions for superior drug encapsulation and precision release

E Dong, Q Huo, J Zhang, H Han, T Cai… - Drug Delivery and …, 2024 - Springer
Nanoscale preparations, such as nanoparticles, micelles, and liposomes, are increasingly
recognized in pharmaceutical technology for their high capability in tailoring the …

[HTML][HTML] Polyamidoamine-stabilized and hyaluronic acid-functionalized gold nanoparticles for cancer therapy

MAA Maki, MS Teng, KF Tan, PV Kumar - OpenNano, 2023 - Elsevier
Gold nanoparticles (AuNPs) are versatile nanomaterials that can be used as drug delivery
systems and photothermal agents for cancer therapy. In this study, we developed a novel …

The influence of drugs solubilities and chitosan-TPP formulation parameters on the mean hydrodynamic diameters and drugs entrapment efficiencies into chitosan …

WM Obeidat, SF Gharaibeh, A Jaradat - AAPS PharmSciTech, 2022 - Springer
Chitosan is a natural, biocompatible polymer. The aim of this work was to study the influence
of drug solubility in 2% v/v acetic acid, formulation parameters, on mean hydrodynamic …

[HTML][HTML] Cytotoxicity enhancement in MCF-7 breast cancer cells with depolymerized chitosan delivery of α-mangostin

Y Herdiana, N Wathoni, S Shamsuddin, M Muchtaridi - Polymers, 2022 - mdpi.com
The application of α-mangostin (AMG) in breast cancer research has wide intentions.
Chitosan-based nanoparticles (CSNPs) have attractive prospects for developing anticancer …

[HTML][HTML] Cytotoxicity Enhancement of α-Mangostin with Folate-Conjugated Chitosan Nanoparticles in MCF-7 Breast Cancer Cells

Y Herdiana, N Wathoni, S Shamsuddin, M Muchtaridi - Molecules, 2023 - mdpi.com
α-mangostin (AM) is a promising natural anticancer agent that can be used in cancer
research. However, its effectiveness can be limited by poor solubility and bioavailability. To …

Microfluidic Platform for Microparticle Fabrication and Release of a Cathepsin Inhibitor

EA Treviño, J Shah, JJ Pearson, MO Platt… - … Engineering Part C …, 2023 - liebertpub.com
Cathepsins are a family of cysteine proteases responsible for a variety of homeostatic
functions throughout the body, including extracellular matrix remodeling, and have been …

Formulation of Resveratrol-Loaded Polycaprolactone Inhalable Microspheres Using Tween 80 as an Emulsifier: Factorial Design and Optimization

R Mahar, A Chakraborty, N Nainwal - AAPS PharmSciTech, 2023 - Springer
Resveratrol (RSV) is a bioactive phytoconstituent that has potential applications in
respiratory diseases. However, poor oral bioavailability is the major hurdle to its clinical use …

[HTML][HTML] Using a systematic and quantitative approach to generate new insights into drug loading of PLGA nanoparticles using nanoprecipitation

SI Hamdallah, R Zoqlam, B Yang, A Campbell… - Nanoscale …, 2024 - pubs.rsc.org
The synthesis of drug-loaded PLGA nanoparticles through nanoprecipitation in
solvent/antisolvent mixtures is well reported but lacks clarity in explaining drug loading …