Mechanisms of 3D cell migration
Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …
Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions
P Lu, D Ruan, M Huang, M Tian, K Zhu… - … and Targeted Therapy, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
The front and rear of collective cell migration
R Mayor, S Etienne-Manneville - Nature reviews Molecular cell biology, 2016 - nature.com
Collective cell migration has a key role during morphogenesis and during wound healing
and tissue renewal in the adult, and it is involved in cancer spreading. In addition to …
and tissue renewal in the adult, and it is involved in cancer spreading. In addition to …
Physical influences of the extracellular environment on cell migration
The way in which a cell migrates is influenced by the physical properties of its surroundings,
in particular the properties of the extracellular matrix. How the physical aspects of the cell's …
in particular the properties of the extracellular matrix. How the physical aspects of the cell's …
[HTML][HTML] Cancer invasion and the microenvironment: plasticity and reciprocity
P Friedl, S Alexander - Cell, 2011 - cell.com
Cancer invasion is a cell-and tissue-driven process for which the physical, cellular, and
molecular determinants adapt and react throughout the progression of the disease. Cancer …
molecular determinants adapt and react throughout the progression of the disease. Cancer …
Cortical contractility triggers a stochastic switch to fast amoeboid cell motility
Summary 3D amoeboid cell migration is central to many developmental and disease-related
processes such as cancer metastasis. Here, we identify a unique prototypic amoeboid cell …
processes such as cancer metastasis. Here, we identify a unique prototypic amoeboid cell …
Focal adhesion–independent cell migration
Cell migration is central to a multitude of physiological processes, including embryonic
development, immune surveillance, and wound healing, and deregulated migration is key to …
development, immune surveillance, and wound healing, and deregulated migration is key to …
Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration
E-cadherin is a major homophilic cell-cell adhesion molecule that inhibits motility of
individual cells on matrix. However, its contribution to migration of cells through cell-rich …
individual cells on matrix. However, its contribution to migration of cells through cell-rich …
Life at the leading edge
AJ Ridley - Cell, 2011 - cell.com
Cell migration requires sustained forward movement of the plasma membrane at the cell's
front or" leading edge." To date, researchers have uncovered four distinct ways of extending …
front or" leading edge." To date, researchers have uncovered four distinct ways of extending …
Reciprocal regulation between resting microglial dynamics and neuronal activity in vivo
Y Li, X Du, C Liu, Z Wen, J Du - Developmental cell, 2012 - cell.com
Microglia are the primary immune cells in the brain. Under physiological conditions, they
typically stay in a" resting" state, with ramified processes continuously extending to and …
typically stay in a" resting" state, with ramified processes continuously extending to and …