Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

Osteoporosis is a prevalent bone disease of the aging population, which is characterized by
a decrease in bone mass because of the imbalance of bone metabolism. Although the …

Abstract N6-methyladenosine (m6A) is the most abundant epigenetic modification in
eukaryotic mRNAs and is essential for multiple RNA processing events during mammalian …

Adipose tissue is an important metabolic organ, the dysfunction of which is associated with
the development of obesity, diabetes mellitus, and cardiovascular disease. The nuclear …

The effects of caloric restriction (CR) on the skeleton are well studied in adult rodents and
include lower cortical bone mass but higher trabecular bone volume. Much less is known …

Increasing evidence supports an association between the skeleton and energy metabolism.
These interactions are mediated by a variety of hormones, cytokines and nutrients. Here, the …

Peri-implantitis is an inflammatory disease affecting tissues surrounding dental implants.
Although it represents a common complication of dental implant treatments, the underlying …

In Western societies, mean body weight has increased dramatically in older people, and a
similar trend exists in Asia. Yet insufficient attention has been directed to the problem of …

Objective—Osteocalcin has been reported to influence insulin secretion in experimental
animals. We investigated whether serum osteocalcin was associated with measures of …

Osteoporosis, a syndrome characterized by thin bones and fractures, has become more
prevalent in both women and men. Established therapies for treating this disorder consist …