Brodmann has pioneered structural brain mapping. He considered functional and
pathological criteria for defining cortical areas in addition to cytoarchitecture. Starting from …

Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …

Animal models of depression are certainly needed but the question in the title has been
raised owing to the controversies in the interpretation of the readout in a number of tests, to …

Understanding the individual variability that comes with the likelihood of developing stress-
related psychopathologies is of paramount importance when addressing mechanisms of …

Depression is one of the most frequent neuropsychiatric diseases in the western world and
its physiological causes are not yet fully understood. Since the available antidepressants …

Early life stress is associated with long-term and pervasive adverse effects on
neuroendocrine development, affecting normal cognitive and emotional development …

Oxidative stress has been claimed a place in pathophysiology of depression; however, the
details of the neurobiology of this condition remains incompletely understood. Recently …

An increasing number of data support the involvement of disturbances in glucose
metabolism in the pathogenesis of depression. We previously reported that glucose and …

Sex differences have been reported in the susceptibility to early life stress and its
neurobiological correlates in humans and experimental animals. However, most of the …

The interrelation of depression and pain is increasingly coming under scrutiny. Although the
lateral habenula (LHb) is widely implicated in the pathogenesis of depression and pain, its …