[HTML][HTML] Fungal cellulases

CM Payne, BC Knott, HB Mayes, H Hansson… - Chemical …, 2015 - ACS Publications
Lignocellulosic biomass has enormous potential to contribute to worldwide energy,
chemical, and material demands in a renewable, sustainable manner. In the United States …

Comparison of yeasts as hosts for recombinant protein production

AM Vieira Gomes, T Souza Carmo, L Silva Carvalho… - Microorganisms, 2018 - mdpi.com
Recombinant protein production emerged in the early 1980s with the development of
genetic engineering tools, which represented a compelling alternative to protein extraction …

Customized yeast cell factories for biopharmaceuticals: from cell engineering to process scale up

A Madhavan, KB Arun, R Sindhu… - Microbial Cell …, 2021 - Springer
The manufacture of recombinant therapeutics is a fastest-developing section of therapeutic
pharmaceuticals and presently plays a significant role in disease management. Yeasts are …

Production of recombinant proteins by yeast cells

E Çelik, P Çalık - Biotechnology advances, 2012 - Elsevier
Yeasts are widely used in production of recombinant proteins of medical or industrial
interest. For each individual product, the most suitable expression system has to be …

Recombinant protein production in yeasts

D Mattanovich, P Branduardi, L Dato, B Gasser… - Recombinant gene …, 2012 - Springer
Recombinant protein production is a multibillion-dollar market. The development of a new
product begins with the choice of a production host. While one single perfect host for every …

Engineering of protein secretion in yeast: strategies and impact on protein production

A Idiris, H Tohda, H Kumagai, K Takegawa - Applied microbiology and …, 2010 - Springer
Yeasts combine the ease of genetic manipulation and fermentation of a microorganism with
the capability to secrete and modify foreign proteins according to a general eukaryotic …

Yeast synthetic biology for the production of recombinant therapeutic proteins

H Kim, SJ Yoo, HA Kang - FEMS yeast research, 2015 - scholarworks.bwise.kr
The production of recombinant therapeutic proteins is one of the fast-growing areas of
molecular medicine and currently plays an important role in treatment of several diseases …

Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

B Gasser, M Saloheimo, U Rinas, M Dragosits… - Microbial cell …, 2008 - Springer
Different species of microorganisms including yeasts, filamentous fungi and bacteria have
been used in the past 25 years for the controlled production of foreign proteins of scientific …

Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae

J Hou, KEJ Tyo, Z Liu, D Petranovic… - FEMS Yeast …, 2012 - academic.oup.com
The yeast Saccharomyces cerevisiae is a widely used cell factory for the production of fuels
and chemicals, and it is also provides a platform for the production of many heterologous …

Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris

H Hohenblum, B Gasser, M Maurer… - Biotechnology and …, 2004 - Wiley Online Library
The expression of heterologous proteins may exert severe stress on the host cells at
different levels. Depending on the specific features of the product, different steps may be rate …