Development of microneedles for antimicrobial drug delivery: A comprehensive review on applications in wound infection management

H Haidari, R Bright, Y Yu, K Vasilev, Z Kopecki - Small Science, 2024 - Wiley Online Library
Microneedles (MNs) have emerged as a promising transdermal antimicrobial delivery
system, providing precise and localized drug delivery while complemented with …

[HTML][HTML] Seeing through the skin: Optical methods for visualizing transdermal drug delivery with microneedles

B Limcharoen, S Wanichwecharungruang… - Advanced Drug Delivery …, 2024 - Elsevier
Optical methods play a pivotal role in advancing transdermal drug delivery research,
particularly with the emergence of microneedle technology. This review presents a …

Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases

Q Bao, X Zhang, Z Hao, Q Li, F Wu, K Wang, Y Li… - Nano-Micro Letters, 2024 - Springer
The eye, a complex organ isolated from the systemic circulation, presents significant drug
delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier …

Nanostructure-Mediated Transport of Therapeutics through Epithelial Barriers

ME Hansen, Y Ibrahim, TA Desai, M Koval - International Journal of …, 2024 - mdpi.com
The ability to precisely treat human disease is facilitated by the sophisticated design of
pharmacologic agents. Nanotechnology has emerged as a valuable approach to creating …

Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer

MS Hussain, E Moglad, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …

Microneedle-mediated drug delivery for neurological diseases

S Tan, Y Wang, X Wei, X Xiao, L Gao - International Journal of …, 2024 - Elsevier
Neurological disorders, including brain injury, brain tumors, and neurodegenerative
diseases, rank as the second leading cause of death worldwide. Exploring effective new …

A Multicomponent Microneedle Patch for the Delivery of Meloxicam for Veterinary Applications

K Miranda-Muñoz, K Midkiff, A Woessner… - ACS …, 2024 - ACS Publications
This study evaluates the use of poly (vinyl alcohol), collagen, and chitosan blends for
developing a microneedle patch for the delivery of meloxicam (MEL). Results confirm …

Harnessing the role of microneedles as sensors: current status and future perspectives

MR Babu, S Vishwas, M Gulati, K Dua, SK Singh - Drug Discovery Today, 2024 - Elsevier
In recent years, microneedles (MNs) have been transformed to serve a wide range of
applications in the biomedical field. Their role as sensors in wearable devices has provided …

Treatment Avenues for Age-Related Macular Degeneration: Breakthroughs and Bottlenecks

P Kumbhar, K Kolekar, S Vishwas, P Shetti… - Ageing Research …, 2024 - Elsevier
Age-related macular degeneration (AMD) is a significant factor contributing to serious vision
loss in adults above 50. The presence of posterior segment barriers serves as chief …

Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs

H Lin, J Liu, Y Hou, Z Yu, J Hong, J Yu, Y Chen… - Drug Delivery and …, 2024 - Springer
Transdermal delivery of peptide drugs is almost impossible with conventional penetration
enhancers because of epidermal barrier function. Microneedle (MN) patches can bypass the …