Drug repositioning is defined as a process to identify a new application for drugs. This
approach is critical as it takes advantage of well-known pharmacokinetics …

Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are the two most important
global parasitic infectious diseases caused by species of Echinococcus granulosus and E …

A novel subtractive manufacturing method to produce bespoke tablets with immediate and
extended drug release is presented. This is the first report on applying fusion laser cutting to …

The co-amorphous solid dispersion (c-ASD) is a useful method to enhance water solubility
of poorly soluble drugs. The objective of this study was to improve the dissolution of …

Solid dispersion (SD) technology has been proved to be one of the most successful
techniques to enhance aqueous solubility of poorly-water soluble drugs. Supercritical fluid …

Betulin dipropionate is a natural compound with high cytotoxicity toward many cancer cells.
The one-step synthesis directly from the birch bark without a separate betulin isolation stage …

Flurbiprofen (FBP), a nonsteroidal anti-inflammatory drug (NSAID), is commonly used to
treat the pain of rheumatoid arthritis, but in prolonged use it causes gastric irritation and …

Solid dispersions are typically binary systems with a hydrophilic matrix polymer and a
lipophilic active substance. During formulation, the drug undergoes a crystalline to …

Purpose Albendazole belongs to BCS-II category whose systemic and local anthelmintic
effectiveness is restricted due to its low water solubility–related dissolution properties. The …

Atorvastatin is a statin group HMG-CoA reductase inhibitor drug that is commonly used to
adverse cardiovascular events and to lower blood total cholesterol and LDL-cholesterol. In …