There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

The endocannabinoid system (ECS), which is composed of the cannabinoid receptors types
1 and 2 (CB1 and CB2) for marijuana's psychoactive ingredient∆ 9-tetrahydrocannabinol (∆ …

There is a growing appreciation that adult hippocampal neurogenesis plays a role in
emotional and cognitive processes related to psychiatric disorders. Although many studies …

Atypical antipsychotics have greatly enhanced the treatment of schizophrenia. The
mechanisms underlying the effectiveness and adverse effects of these drugs are, to date, not …

The neurogenesis hypothesis of depression posits (1) that neurogenesis in the subgranular
zone of the dentate gyrus is regulated negatively by stressful experiences and positively by …

Neurogenesis in the adult dentate gyrus (DG) of the hippocampus occurs constitutively
throughout postnatal life, and the rate of neurogenesis within the DG can be altered under …

Biologists long believed that, once development is completed, no new neurons are
produced in the forebrain. However, as is now firmly established, new neurons can be …

The original definition of atypical antipsychotic drugs (APD) was drugs that are effective
against positive symptoms in schizophrenia with no or little extrapyramidal symptoms (EPS) …

Generalized cognitive impairments are stable deficits linked to schizophrenia and key
factors associated with functional disability in the disorder. Preclinical data suggest that …

We have reported that hydrogen (H 2) acts as an efficient antioxidant by gaseous rapid
diffusion. When water saturated with hydrogen (hydrogen water) was placed into the …