Methane monooxygenases (MMOs) are enzymes that catalyze the oxidation of methane to
methanol in methanotrophic bacteria. As potential targets for new gas-to-liquid methane …

In recent years, significant progress has been made in understanding the geometric and
electronic structures of the active sites of non-heme iron enzymes and the contributions of …

▪ Abstract Desaturation of a fatty acid first involves the enzymatic removal of a hydrogen from
a methylene group in an acyl chain, a highly energy-demanding step that requires an …

Dioxygen activation by metalloenzymes generally proceeds through one of two
fundamentally different routes. Some enzymes, such as the ferric ion containing intradiol …

The 2.2 Å crystal structure of the 251K α2β2γ2 dimeric hydroxylase protein of methane mono-
oxygenase from Methylococcus capsulatus (Bath) reveals the geometry of the catalytic di …

Reactions of dioxygen with ferrous ion and its complexes occur widely in nature. In biology,
the best known and probably most studied systems are proteins that contain one or more …

Methanotrophic bacteria are capable of using methane as their sole source of carbon and
energy. The first step in methane metabolism, the oxidation of methane to methanol, is …

Aerobic life is possible because the molecular structure of oxygen (O2) makes direct
reaction with most organic materials at ambient temperatures an exceptionally slow process …

The field of isotope effects has expanded exponentially in the last decade, and researchers
are finding isotopes increasingly useful in their studies. Bringing literature on the subject up …

Methanotrophs are bacteria that live on methane as their only source of carbon. 1 The first
step in their utilization of this simplest of all hydrocarbons is its selective conversion to …