The past, present and future of flow cytometry in central nervous system malignancies

E Vartholomatos, G Vartholomatos, GA Alexiou… - Methods and …, 2021 - mdpi.com
Central nervous system malignancies (CNSMs) are categorized among the most aggressive
and deadly types of cancer. The low median survival in patients with CNSMs is partly …

Advances in intraoperative flow cytometry

MV D'Amato Figueiredo, GA Alexiou… - International Journal of …, 2022 - mdpi.com
Flow cytometry is the gold-standard laser-based technique to measure and analyze
fluorescence levels of immunostaining and DNA content in individual cells. It provides a …

Detection of cancer cells and tumor margins during colorectal cancer surgery by intraoperative flow cytometry

VK Georvasili, GS Markopoulos, A Batistatou… - International Journal of …, 2022 - Elsevier
Abstract Background Flow Cytometry is an analytical technique for the precise quantification
of cellular phenotype. Intraoperative Flow Cytometry (iFC) utilizes flow cytometry for DNA …

Touch imprint intraoperative flow cytometry as a complementary tool for detailed assessment of resection margins and tumor biology in liver surgery for primary and …

GS Markopoulos, GK Glantzounis, AC Goussia… - Methods and …, 2021 - mdpi.com
Liver resection is the main treatment for primary and metastatic liver tumors in order to
achieve long-term survival with good quality of life. The ultimate goal of surgical oncology is …

Rapid assessment of resection margins during breast conserving surgery using intraoperative flow cytometry

G Vartholomatos, H Harissis, M Andreou, V Tatsi… - Clinical Breast …, 2021 - Elsevier
Background Positive margins are the most important factor for recurrence of the disease
after breast-conserving surgery. Several methods have been developed throughout the …

Accurate characterization of bladder cancer cells with intraoperative flow cytometry

A Paliouras, GS Markopoulos, S Tsampalas… - Cancers, 2022 - mdpi.com
Simple Summary Bladder cancer is a malignancy that predominantly affects male patients.
Surgical treatment is the first option for clinical management and cancer cell characterization …

Resection margins assessment by intraoperative flow cytometry in pancreatic cancer

GS Markopoulos, A Goussia, CD Bali… - Annals of Surgical …, 2022 - Springer
We read with great interest the landmark article by Shah et al. which efficiently underlines
the importance of resection margins in surgery for pancreatic ductal adenocarcinoma …

Assessment of gliomas' grade of malignancy and extent of resection using intraoperative flow cytometry

G Vartholomatos, GS Markopoulos, E Vartholomatos… - Cancers, 2023 - mdpi.com
Simple Summary Intraoperative Flow Cytometry (iFC) is a new technique that can help
assess the malignancy grade, diagnose tumor type, and evaluate resection margins during …

The emerging role of intraoperative flow cytometry in intracranial tumor surgery

GA Alexiou, G Vartholomatos, T Kobayashi… - Clinical neurology and …, 2020 - Elsevier
Intraoperative flow cytometry has been recently emerged as a novel and promising tool for
intracranial tumor surgery. Herewith, we discuss the role of intraoperative flow cytometry for …

[HTML][HTML] Past, present and future of flow cytometry in breast cancer–a systematic review

M Andreou, E Vartholomatos, H Harissis… - EJIFCC, 2019 - ncbi.nlm.nih.gov
Breast cancer is the most common malignancy in women worldwide. In this systematic
review 28 studies were taken into account, in order to evaluate the role of DNA content and …