Systematic literature review informing the 2022 update of the EULAR recommendations for the management of ANCA-associated vasculitis (AAV): part 2-treatment of …

B Sanchez-Alamo, JH Schirmer, B Hellmich… - Rmd Open, 2023 - rmdopen.bmj.com
Objective To summarise and update evidence to inform the 2022 update of the European
Alliance of Associations of Rheumatology (EULAR) recommendations for the management …

Histopathological prognostic factors in ANCA-associated glomerulonephritis.

C Boud'hors, MC Copin, S Wacrenier, GB Piccoli… - Autoimmunity …, 2022 - Elsevier
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are a group of
multisystemic autoimmune diseases characterized by necrotizing inflammation of small …

Clinical features and prognosis of MPO-ANCA and anti-GBM double-seropositive patients

X Hu, C Shen, T Meng, JD Ooi… - Frontiers in …, 2022 - frontiersin.org
Background Several lines of evidence implicate that there are distinct differences between
patients with myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA) and anti …

Novel aspects in the pathophysiology and diagnosis of glomerular diseases

A Kronbichler, I Bajema, D Geetha… - Annals of the rheumatic …, 2023 - ard.bmj.com
Immune deposits/complexes are detected in a multitude of tissues in autoimmune disorders,
but no organ has attracted as much attention as the kidney. Several kidney diseases are …

Complement components C3 and C4 indicate vasculitis manifestations to distinct renal compartments in ANCA-associated glomerulonephritis

S Hakroush, D Tampe, P Korsten, P Ströbel… - International Journal of …, 2021 - mdpi.com
Acute kidney injury (AKI) is a common and severe complication of antineutrophil cytoplasmic
antibodies (ANCA)-associated vasculitis (AAV) causing progressive chronic kidney disease …

The complement system in antineutrophil cytoplasmic antibody-associated vasculitis: pathogenic player and therapeutic target

M Mazzariol, L Manenti, A Vaglio - Current Opinion in …, 2023 - journals.lww.com
The increased circulating levels of some complement components–as well as the
consumption of others–in patients with AAV suggested a systemic activation of the …

[HTML][HTML] Long-Term Renal Survival in Antineutrophil Cytoplasmic Antibody–Associated Glomerulonephritis With Complement C3 Deposition

R Oba, G Kanzaki, T Sasaki, Y Okabayashi… - Kidney International …, 2021 - Elsevier
Introduction Recent studies have revealed the pivotal role of complement activation in the
pathogenesis of antineutrophil cytoplasmic antibody–associated glomerulonephritis (ANCA …

Serum Complement C4 Levels Are a Useful Biomarker for Predicting End-Stage Renal Disease in Microscopic Polyangiitis

S Matsuda, K Oe, T Kotani, A Okazaki… - International Journal of …, 2023 - mdpi.com
This study aimed to evaluate the risk factors for end-stage renal disease (ESRD) in
microscopic polyangiitis (MPA). In total, 74 patients with MPA were enrolled, and we …

[HTML][HTML] How the availability of anti-C5a agents could change the management of antineutrophil cytoplasmic antibody-associated vasculitis

D Roccatello, R Fenoglio, V Oddone… - Kidney and Blood …, 2022 - karger.com
Background: Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a cluster of
potentially life-threatening disorders, often involving the kidney with a necrotizing crescentic …

Association of Bowman's capsule rupture with prognosis in patients with lupus nephritis

T Duan, X Zhu, Q Zhao, L Xiao, L He, H Liu, A Chen… - Journal of …, 2022 - Springer
Background and objective Lupus nephritis is one of the most severe manifestations of
systemic lupus erythematosus. The clinical and prognostic significance of Bowman's …