We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Hepatitis B virus (HBV) is an endemic, chronic virus that leads to 800000 deaths per year.
Central to the HBV lifecycle, the viral core has a protein capsid assembled from many copies …

While the structure of a multitude of viral particles has been resolved to atomistic detail, their
assembly pathways remain largely elusive. Key unresolved issues are particle nucleation …

The process of genome packaging in most of viruses is poorly understood, notably the role
of the genome itself in the nucleocapsid structure. For simple icosahedral single-stranded …

We consider a statistical mechanical model of a generic flexible polyelectrolyte, comprised
of identically charged monomers with long-range electrostatic interactions and short-range …

Single-stranded RNA viruses efficiently encapsulate their genome into a protein shell called
the capsid. Electrostatic interactions between the positive charges in the capsid protein's N …

The current SARS-CoV-2 pandemic highlights our fragility when we are exposed to
emergent viruses either directly or through zoonotic diseases. Fortunately, our knowledge of …

Single-stranded RNA viruses efficiently encapsulate their genome into a protein shell called
the capsid. Understanding the physical principles underlying the formation of virus capsid …

Realistic evolutionary fitness landscapes are notoriously difficult to construct. A recent
cutting-edge model of virus assembly consists of a dodecahedral capsid with 12 …

The spontaneous encapsulation of genomic and non-genomic polyanions by coat proteins
of simple icosahedral viruses is driven, in the first instance, by electrostatic interactions with …