The abundant adrenal C19 steroid 11β-hydroxyandrostenedione (11OHA4) has been
written off as a dead-end product of adrenal steroidogenesis. However, recent evidence has …

This review is an attempt to describe advancements in the electrochemistry of cytochrome
P450 enzymes (EC 1.14. 14.1) and to study molecular aspects and catalytic behavior of …

Coenzyme Q (CoQ) is a redox active lipid that plays a central role in cellular homeostasis. It
was discovered more than 60 years ago because of its role as electron transporter in the …

The growing preference for producing cytochrome P450-mediated natural products in
microbial systems stems from the challenging nature of the organic chemistry approaches …

Cytochrome P450 enzymes (P450s or CYPs) catalyze an enormous variety of oxidative
reactions in organisms from all major domains of life. Their monooxygenase activity relies on …

In humans, reticularis cells of the adrenal cortex fuel the production of androgen steroids,
constituting the driver of numerous morphological changes during childhood. These steps …

Abstract Cytochrome b5 (cyt b5) is a small hemoprotein that plays a significant role in the
modulation of activities of an important steroidogenic enzyme, cytochrome P450 17α …

This paper reviews state-of-the-art knowledge on steroid biosynthesis pathways in the pig
and provides an updated characterization of the porcine genes involved in these pathways …

The comprehensive evaluation of the adrenal steroidogenic pathway, given its complexity,
requires methodology beyond the standard techniques currently employed. Advances in LC …

Androgens play an important role during the development of both normal prostate
epithelium and prostate cancer and variants of genes involved in androgen metabolism may …