Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

Fibroblasts are crucial components of the skin structure. They were traditionally believed to
maintain the skin's structure by producing extracellular matrix and other elements. Recent …

Primary mitochondrial diseases result from mutations in nuclear DNA (nDNA) or
mitochondrial DNA (mtDNA) genes, encoding proteins crucial for mitochondrial structure or …

The aging process is linked to numerous cellular changes, among which are modifications
in the functionality of dermal fibroblasts. These fibroblasts play a crucial role in sustaining …

Health is strongly affected by aging and lifespan-modulating interventions, but the molecular
mechanisms of mortality regulation remain unclear. Here, we conducted an RNA-seq …

Chronic stress is a common cause of hair loss, involving inflammatory responses and
changes in cellular signaling pathways. This study explores the mechanism of action of the …

Aging is characterized by a gradual decline in function, partly due to accumulated molecular
damage. Human skin undergoes both chronological aging and environmental degradation …

DNA methylation is an important epigenetic mechanism that helps define and maintain
cellular functions. It is influenced by many factors, including environmental exposures …

Primary mitochondrial diseases result from mutations in nuclear DNA (nDNA) or
mitochondrial DNA (mtDNA) genes, encoding proteins for crucial mitochondrial structure or …