Epigallocatechin gallate is the most abundant composition of the tea catechins and is
thought to be responsible for the majority of biological activity of green tea extracts such as …

The problem of pesticides is not new and its exposure to human due to indiscriminate use is
largely associated with the health related problems including neurotoxicological alterations …

Cobalt chloride (CoCl2) is a well-known hypoxia mimetic mediator that induces hypoxia-like
responses. CoCl2, a mediator confirmed to alleviate hypoxia-inducible factor-1 (HIF-1), has …

Human beings are exposed to various environmental xenobiotics throughout their life
consisting of a broad range of physical and chemical agents that impart bodily harm. Among …

The plethora of literature has supported the potential benefits of Resveratrol (RV) as a life-
extending as well as an anticancer compound. However, these two functional discrepancies …

Nerve growth factor (NGF) and its precursor form, proNGF, are critical for neuronal survival
and cognitive function. In the brain, proNGF is the only detectable form of NGF …

Current research and drug development for multiple sclerosis (MS) is fully influenced by the
self–nonself (SNS) model of immunity, suggesting that breakage of immunological tolerance …

Expression of various cytochrome P450s (CYPs) in mammalian brain cells is well
documented. However, such studies are hampered in neural/glial cells of human origin due …

Microneurotrophins, small-molecule mimetics of endogenous neurotrophins, have
demonstrated significant therapeutic effects on various animal models of neurological …

Cognitive deficit is one of the most serious complications of cranial radiotherapy of head and
neck cancers. However, the underlying mechanism of this cognitive impairment remains …